The d-enantiomers of amphetamine and methamphetamine have certain advantages. Dextroamphetamine, which is the more potent stereoisomer of RS-amphetamine, is very effective at preventing the reuptake of neurotransmitters, resulting in more mental stimulation than physical stimulation.
It is considered a functional therapeutic agent due to its low effect on noradrenaline and 5-hydroxytryptamine receptors. Compared to the classic mixture of RS-amphetamine, dexamphetamine has a stronger interaction with the dopamine receptor, which leads to a more pronounced central action and less peripheral action.
It takes about 20 to 60 minutes to take effect, and the effect lasts for about 3 to 6 hours. Recreational doses of D-amphetamine have fewer side effects than the enantiomeric mixture, such as headache, chills/sweating, allergic reactions, nausea/dyspepsia, insomnia/anxiety. Moreover, the risk of cytotoxic potential is reduced since the effects of n-hydroxyamphetamine and other D-form metabolic products are minimal.
It is considered a functional therapeutic agent due to its low effect on noradrenaline and 5-hydroxytryptamine receptors. Compared to the classic mixture of RS-amphetamine, dexamphetamine has a stronger interaction with the dopamine receptor, which leads to a more pronounced central action and less peripheral action.
It takes about 20 to 60 minutes to take effect, and the effect lasts for about 3 to 6 hours. Recreational doses of D-amphetamine have fewer side effects than the enantiomeric mixture, such as headache, chills/sweating, allergic reactions, nausea/dyspepsia, insomnia/anxiety. Moreover, the risk of cytotoxic potential is reduced since the effects of n-hydroxyamphetamine and other D-form metabolic products are minimal.