Amination 2bromo 3chloropriophenone? How ?

[Moneymaker2011]

Hi, listen, the amination with 2bromo 3 chloropriophenone looks the same as with the others? How does it look like I use dmso for amination? Also I can use methylamine in water as it mixes with DMSO or is it better to use methyl in ethanol or methanol?

 

[HIGGS BOSSON]

Synthesis can be carried out according to this technique, only instead of methylbromoketone use chlorobromketone (2bromo 3 chloropriophenone)

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/index.php?threads/synthesis-of-mephedrone-in-nmp-large-scale.231/

 

[dark_side_of_chemistry]

which is 25 min 55 degrees. at dso also at a temperature of up to 40 degrees before methylamine? as an extractor I can use dcm or better toluene? after phase separation, wash the organic phase with water? how to add acid with such amounts? at once or in batches? my theoretical assumption is that after the amination of hydrochloric acid you will need to add 1450ml

 

[WillD]

yes
You can use what's available
use electronic pH-meter or indicator paper to pH 5.5-6

 

[dark_side_of_chemistry]

Thx