how best to calculate powder for pill pressing/preparation
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Pregabalin how best to calculate powder for pill pressing/preparation
- Thread starter DrGodMan
- Start date
What exactly are you talking about? Pills are made with a mixture of different "excipients" you can buy cheaply (google novapress). Why would you break a tablet to press it again?
Search "TDP LFA Tablet press" on youtube and it will explain everything to you
However, you also need a machine to press parts. These hand press things are whack.
Search "TDP LFA Tablet press" on youtube and it will explain everything to you
However, you also need a machine to press parts. These hand press things are whack.
Hey DrGodMan,
I'm afraid this answer is a little late, but you've probably already found an answer by now, haven't you?
So I'm assuming that you mean "calculate", right?
To do this, you first need to know what the total weight of a tablet will be -> test run with fillers only, and then weigh tablet
Now that you know how much a tablet will weigh, you can calculate it quite easily;
e.g.
- one tablet weighs a total of 350mg
- you want ~50mg active ingredient per tablet
-> per 50mg you need 300mg filler
- let's say you have 100g of active ingredient that you want to press into tablets
- so you should get about 2,000 pieces (100g / 0.05g)
- 2000 x 0.3g = 600g filler
Of course, it is important that you mix everything thoroughly for a long time to minimise the difference/fluctuation in the active ingredients of the individual tablets.
Hope this helps you. Or maybe the next person who asks this question XD
I'm afraid this answer is a little late, but you've probably already found an answer by now, haven't you?
So I'm assuming that you mean "calculate", right?
To do this, you first need to know what the total weight of a tablet will be -> test run with fillers only, and then weigh tablet
Now that you know how much a tablet will weigh, you can calculate it quite easily;
e.g.
- one tablet weighs a total of 350mg
- you want ~50mg active ingredient per tablet
-> per 50mg you need 300mg filler
- let's say you have 100g of active ingredient that you want to press into tablets
- so you should get about 2,000 pieces (100g / 0.05g)
- 2000 x 0.3g = 600g filler
Of course, it is important that you mix everything thoroughly for a long time to minimise the difference/fluctuation in the active ingredients of the individual tablets.
Hope this helps you. Or maybe the next person who asks this question XD