Is this viable? Okay it’s rough but bear with me….
I have 2,5-dimethoxybenzaldehyde, nitromethane, and LAH all in enough quantity for make a fair amount of 2c-h.
I also have azeotropic H2SO4 and something like 37% Hcl acid, for if I don’t want to continue straight away, however, and here is the question, if I wanted to make 2c-e from this, could I then use the obtained 2c-h, react it with acetaldehyde to form the imine intermediate and then simply reduce (either again with LAH - although more likely NaBH4)?
Would this be enough to ethylate the prior phenethylamine?
I have 2,5-dimethoxybenzaldehyde, nitromethane, and LAH all in enough quantity for make a fair amount of 2c-h.
I also have azeotropic H2SO4 and something like 37% Hcl acid, for if I don’t want to continue straight away, however, and here is the question, if I wanted to make 2c-e from this, could I then use the obtained 2c-h, react it with acetaldehyde to form the imine intermediate and then simply reduce (either again with LAH - although more likely NaBH4)?
Would this be enough to ethylate the prior phenethylamine?