how can i extract from loratadine and pseudoephedrine pills?

caydiantak

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i found pseudoephedrine (lot more)loratadine(5mg) pills at my country. How do i make it into pseudoephedrine salt?
 

emanuel852

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h

Hi, did you have any solution? I have the same problem
 

hacke8

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Loratadine is insoluble in water. You can use ethanol or methanol to soak the pills, filter them, and filter out some impurities that are insoluble in ethanol. After evaporation of ethanol, add distilled water and filter. Loratadine is insoluble in water. The filtered liquid is adjusted to alkali ph10+, extracted, dried, and hydrogen chloride gas. Filter.
 

emanuel852

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hello but I need to separate Loratadine from pseudoephedrine, Loratadine is insoluble in water and pseudoephedrine is also insoluble in water.
So I don't know how to do it
 
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hacke8

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You didn't read my reply carefully. Ephedrine is soluble in water and ethanol. Lorata is insoluble in water. After evaporation of ethanol, add water and filter, and loratadine will be left on the filter cake.
 

emanuel852

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great you are a crack buddy my last question is do I let the ethanol evaporate in a beaker over a heat producing burner?
 

hacke8

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There is no need for reflux. It is enough to evaporate ethanol under normal pressure. But don't be too dry, because it is not easy to dissolve after adding water. It's as best as nutritious soil.
 
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