info

[Basil587]

yes

 

[DavidDavison2021]

I'm listening

 

[madmoney69]

1. Add the following Successively into the reaction bottle:
1kg of adb main material,
3L of DMF, (CAS 68-12-2)
850g of anhydrous potassium carbonate, (CAS584-08-7)
680g of bromobutane (CAS 109-65-9)
2. Raise the temperature of the reaction flask to 70-80°C for 5 hours.
3. After the reaction, the solution ① is obtained, and it is cooled to room temperature.
4. Prepare the bucket in advance, add 15L of water,
5. Pour the solution ① into the bucket and cool to room temperature
6. Filter the solid, and then repeatedly wash with water several times until the solution is neutral (pH
test paper can be used to test the pH of the solution),
7. Dry the neutral solution. you will get adb b.

 

[DavidDavison2021]

I seen this a couple months back, I didnt think is was legit after asking a buddy who runs a lab.

 

[Jailhmp]

Who can assist me with this with some videos showing the process

 

[Jailhmp]

I will
is there any videos for this please

 

[orgasmatron]

Does anyone know if the reaction needs cooling at any point or is only heating necessary?
Can DMA ( N,N-dimethylacetamide )be used instead of DMF?
Is product loss during water washes a concern?

 

[BackstagePanther]

What is this ADB material? We can find a precursor (2S)-2-[(5-bromo-1-butyl-1H-indazol-3-yl)formamido]-3,3-dimethylbutanamide
is this procedure described here going to work with that precursor?

 

[WillD]

You are talking about the end substance, not a precursor