Question protonitazene and fentanyl what the different?
- Thread starter mrshootyouup
- Start date
Protonitazine is 2-3x as strong and has an indole core molecule but they act on the same receptor. Even people thinking they are taking fentanyl could easily overdose on it. Thanks Google. See you in hell 
where the people you poison with it will fuck you in the ass for eternity 
where the people you poison with it will fuck you in the ass for eternity 
Protonitazene and fentanyl are both potent synthetic opioids, but they differ in their chemical structure, potency, and potentially their effects. Fentanyl belongs to the class of phenylpiperidine opioids. Its chemical structure is characterized by a piperidine ring connected to a phenyl group. Protonitazene is a member of the benzimidazole opioid class. Its structure includes a benzimidazole ring, which is distinct from fentanyl’s phenylpiperidine structure.
Fentanyl is approximately 50 to 100 times more potent than morphine. This high potency contributes to its effectiveness in pain management but also its risk of overdose. Protonitazene is reported to be even more potent than fentanyl. Early studies and anecdotal reports suggest it could be several times more potent, but exact comparisons can vary.
Both fentanyl and protonitazene are powerful pain relievers due to their action on mu-opioid receptors in the brain. Both drugs can induce euphoria, which contributes to their potential for abuse. The intensity of euphoria might be similar, though individual experiences can vary. Due to its higher potency, protonitazene might induce stronger or more rapid euphoria. Both opioids significantly depress respiratory function, which is a major risk factor for fatal overdose. Protonitazene’s higher potency increases this risk.
Fentanyl has a rapid onset and short duration of action. The pharmacokinetic profile of protonitazene is less well-documented, but it may have similar or even faster onset with potentially longer duration due to its potency.
While protonitazene and fentanyl share many similarities, protonitazene is potentially more potent and thus poses a greater risk for overdose. Their different chemical structures also mean they may have slightly different pharmacological profiles and side effect profiles.
Fentanyl is approximately 50 to 100 times more potent than morphine. This high potency contributes to its effectiveness in pain management but also its risk of overdose. Protonitazene is reported to be even more potent than fentanyl. Early studies and anecdotal reports suggest it could be several times more potent, but exact comparisons can vary.
Both fentanyl and protonitazene are powerful pain relievers due to their action on mu-opioid receptors in the brain. Both drugs can induce euphoria, which contributes to their potential for abuse. The intensity of euphoria might be similar, though individual experiences can vary. Due to its higher potency, protonitazene might induce stronger or more rapid euphoria. Both opioids significantly depress respiratory function, which is a major risk factor for fatal overdose. Protonitazene’s higher potency increases this risk.
Fentanyl has a rapid onset and short duration of action. The pharmacokinetic profile of protonitazene is less well-documented, but it may have similar or even faster onset with potentially longer duration due to its potency.
While protonitazene and fentanyl share many similarities, protonitazene is potentially more potent and thus poses a greater risk for overdose. Their different chemical structures also mean they may have slightly different pharmacological profiles and side effect profiles.
- By mrshootyouup
But how I understanding from your opinion brother the effect and euphoria it's almost similar like fentanyl? But the time of euphoria it's even longer then fentanyl euphoria? In your opinion for safe use pure protonitazene how much need to be cutted? Like 1g how much I need to Cutt to make a safe use and very good quality in your opinion brother and what stuff best to cut?
- By Paracelsus
I'm unlikely to be able to please you with simple and clear answers. Protonitazene is a fairly new substance, plus many factors affect the effects and safety for a particular person, for example, the way of use, individual tolerance, the quality of the substance, etc.
In animal studies, the effective dose (ED50) of Protonitazene is estimated as a e 0.008 mg/kg.
I've seen unconfirmed recommendations from users online were advised to try 1 mg of Protonitazene per 10 ml of water or ethanol.
In any case, these figures should not yet be considered as safe and reasonable recommendations.
In animal studies, the effective dose (ED50) of Protonitazene is estimated as a e 0.008 mg/kg.
I've seen unconfirmed recommendations from users online were advised to try 1 mg of Protonitazene per 10 ml of water or ethanol.
In any case, these figures should not yet be considered as safe and reasonable recommendations.
I have tried protonitazene and metonitazene a couple of years ago (shipped from China) because at that time the fent quality went down fast after the export was banned in China from U.S. government pressure. I did not enjoy either of them one bit. The taste was absolutely horrbible, I remember almost gagging. It is possible that what I tried was not what I thought it was, since I did not have any way to test it.