Verification of Lysergic Acid Derivatives' Solubility – Are My Values Correct?

[fuzzypuma]

Hello everyone,

I have compiled a table showing the solubility of various lysergic acid derivatives in different solvents and would appreciate your feedback.
Does anyone have reliable literature sources or personal experimental data?

Here is my current table:

Lysergic Acid Derivative	Water (neutral)	Water (acidic, pH 3)	Ethanol	Methanol	Isopropanol (IPA)	Acetone	Chloroform	Diethyl Ether	Dichloromethane
Free Lysergic Acid (Base)	Poorly soluble		Slightly soluble	Moderately soluble	Moderately soluble	Moderately soluble	Moderately soluble	Very poorly soluble	Moderately soluble
Lysergic Acid Sulfate	Highly soluble	Precipitates	Moderately soluble	Moderately to well soluble	Moderately to poorly soluble	Moderately soluble	Insoluble	Insoluble	Insoluble
Lysergic Acid Hydrochloride	Well soluble	Highly soluble	Moderately soluble	Moderately soluble	Poorly soluble	Poorly soluble	Insoluble	Insoluble	Insoluble
Lysergic Acid Tartrate	Highly soluble	Highly soluble	Moderately soluble	Well soluble	Well soluble	Well soluble	Insoluble	Insoluble	Insoluble
Lysergic Acid Maleate	Moderately soluble	Well soluble	Moderately soluble	Moderately soluble	Moderately soluble	Moderately soluble	Insoluble	Very poorly soluble	Insoluble

I appreciate any corrections or additions and look forward to your expertise!

Thanks & best regards!

 

[loadingST]

Hello, very good information, one of my future projects is to try to prepare some, information like that is always very helpfull, can you give us more details abaut the conditions in which these salts are formed, for example how sensitive is lsd to acids,bases,solvents etc

 

[fuzzypuma]

i mean "D-lysergic acid" not LSD-25, D-lysergic acid is the precursor for LSD-25.