Destillation of Amphetamin Base in Vacuum

[Sasha89]

Is it possible to destill amphetamin freebase in vacuum without adding of water like in a normal steam destillation?
If yes, can it be done in a rotovap and on whitch temperature is the boiling point, for example at 100mbar vacuum ? Does anybody know?

 

[G.Patton]

This substance become volatile with water and doesn't take high temperature for distillation.

 

[Sasha89]

I know that, but I've heard that the distillation is faster if you do it in a vacuum, in this case with water, is this right?

 

[G.Patton]

Yes, you can try. Use water trap on the vacuum line to save your vacuum pump.

 

[Sasha89]

Ok thank you very much

 

[Saul]

people say that the free base can be extract with dcm or by using steam destilation .
if I choose for the second one do I need first add water to the substance ?

 

[G.Patton]

Hi, extract from what exactly?

 

[Saul]

the black freebase liquid after boiling with HCl for two hours.

 

[G.Patton]

Amphetamine free base is transparent or has yellow tint. Did you boiled free base with HCl and your amphetamine free base solution is turned black? Probably you overoxidized your product and it is spoiled.

 

[Saul]

after steam distillation it is very light yellow

 

[UWe9o12jkied91d]

That is what we like to see

 

[G.Patton]

Can you explain exactly procedure, which you want to do please. I still don't understand completely what you wanna do. Do you wanna distill amph free base directly from reaction mass after amph synthesis?

 

[Saul]

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/attachments/lbcfyxhuxr-jpg.8207/?hash=e7ffa8dfeda7c69c4449d436ad1b8f63