Which route used to synthesize MDMA has the strongest effects?

[bitcoinup2020]

I would like to ask from those who know what is the most effective and powerful route for MDMA synthesis.

 

[testint]

Take two

 

[The-Hive]

250 g piperonal is dissolved in 900 ml 95% EtOH and there is added 150 mls nitroethane, 10g methylamine hydrochloride and 8g sodium carbonate. After a brief stirring the mixture is left in a dark place for 2 weeks. It is then poured into 7 L water, the precipitate filtered, washed with water and air-dried. Recrystallization from small qtties of EtOH. Yield 87%.

 

[craris100]

Really interesting procedure. Its possible to do it for big quantities?

 

[The-Hive]

even better on a 1kg scale over head stirr (drill) get about 900g if done correctly

 

[Macondor]

precipitate in water? what? an oil? a carbonate? what is this? a M-styrene?
i see that a lot of reaction can be done in long time with out too much reagents , what is the thing here?

 

[The-Hive]

Research you’ll find out….

 

[Macondor]

yea this is for the intermediate.

3,4-Methylenedioxyphenyl-2-Nitropropene from Piperonal, Nitroethane and NaOH - [www.rhodium.ws]

 

[The-Hive]

 

[btcboss2022]

NaBH4 reduction

 

[bitcoinup2020]

Thank you very much, teacher.

 

[Jordan Belfort]

My opinion, use a method with the least stereoselective like NaBH4 as mentioned before and clean the excess NaBH4 with a non-polar solvent.

 

[bitcoinup2020]

Thank you very much

 

[AKWA]

Thought the good old Al metal amalgam reduction was preferred for its strong product

 

[Pororo]

me - old junky but me still remember simple scientist fact..... various routes leads to different carbon isotopes in final product....
but not sure if various carbon isotopes lead to different quality