4′-methylpropiophenone bromination

  1. WillD

    4′-Methylpropiophenone bromination to 2-bromo-4'-methylpropiophenone. Large scale.

    Reaction scheme: Reagents: 4′-Methylpropiophenone (cas 5337-93-9) 1000 g; Hydrobromic acid 48% aq. 1140 g or 765 ml; Hydrogen peroxide (H2O2) 35% 328 g or 290 ml; Sodium bicarbonate (NaHCO3); Distilled water; Equipment and glassware: Three necked round bottom flask 5 L; Retort stand and...
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