Where I can find 4'-Methylpropiophenone and 2-Bromo-4'-methylpropiophenone?
Due to 4'-Methylpropiophenone CAS 5337-93-9 illegal status (controlled in many countries), it's almost impossible to find it on the DarkNet market. However, there is another direct precursor for mephedrone (4-MMC)...
2-Bromo-4'-methylpropiophenone synthesis (CAS 1451-82-7) from 4'-methylpropiophenone with HBr/H2O2
https://bbgate.com/threads/bromination-of-4-methylpropiophenone-with-hbr-h2o2-large-scale.215/
4'-methylpropiophenone iodination with iodine/cooper (II) oxide
https://bbgate.com/threads/iodination-of-4-methylpropiophenone-with-iodine-cooper-ii-oxide-large-scale.218/
We'll consider mephedrone (4MMC) synthesis in this article. Dichloromethane (DCM) is used as a solvent. It has a low boiling point (~40 °C) and synthesis procedures take a little time.
Work conditions:
Air temperature 20-24 ºC;
Relative humidity <60%;
Well-ventilated room (with air...
Reaction scheme:
Reagents:
4'-Methylpropiophenone (cas 5337-93-9) 5 kg;
Сooper(II) oxide (CuO) 2.7 kg;
Isopropyl alcohol (IPA) 50 l;
Iodine 6.5 kg;
Equipment and glassware:
100 L Batch reactor, which is equipped with drip funnel, top stirrer, thermometer, temperature control system...