reductive amination

Hey guys, I have a synth coming up (currently waiting for the main reagent) and the synth calls for both a water bath and rotovap. So to put my situation into perspective it’s important to say that I am learning chemistry as a hobby and I do not make things for people other than myself! Okay...

hey folks, to encourage a more ecological sustainable method for amine reduction than Al/Hg, i want to present you the aluminium-gallium-amalgan method. Basically you can just use al-ga amalgan instead the mercury one and that's it. Actually a ratio of 1:1 between reactant and amalgan, while a...

Hello. You can put Phenyl-2-Propanone (P2P), excess Ethylamine freebase, 70% Ethanol water, some Formic acid, H2CO3 (Seltzer water, Carbonic acid), and Palladium on carbon in a ice cooled round bottom flask or flat bottom boiling flask. Male sure the pH is around 4 and use the pH indicators. You...

You can get safrole and hydrate it using dilute phosphoric acid to get MDP2Pol (3,4-MethyleneDioxyPhenyl-2-Propanol). If you use dilute sulfuric acid, the MDP2Pol will rearrange into MDP1Pol (3,4-MethyleneDioxyPhenyl-1-Propanol). Then, you can use manganese dioxide or PCC to oxidize it to MDP2P...

Chloroform can react with chlorine gas and iron powder to form carbon tetrachloride and forms hydrogen chloride as a byproduct. Thiophene is brominated to 2-Bromothiophene with bromine in Carbon Tetrachloride. 2-Bromothiophene can react with ethyl acetoacetate and sodium ethoxide and using...

Well Howdy there folks! There’s a lot of info and conversations and loosely, reliable syntheses on many forums discussing using 2 particular reagents, but I need something objective. I’m looking for this “gold standard” synth everyone is having success with using Sodium Borohydride and...

NaBH4 is added to RBF and suspended in DCE or THF 3 molar equivalent Glacial acetic acid are added drop wise and the mixture was stirred until no more Hydrogen gas evolved. and after this can I vacuum distillate solvent with little heat and take it to dryness?

Take pure to Toluene and synthesize Benzyl Chloride by adding TCCA (trichloroisocyanuric acid) and putting it in sunlight and using lithium bromide as a catalyst. Getting benzyl chloride might take hours to days. The lithium bromide makes it go faster so it could take hours instead of days.. You...