tryptamine

  1. B

    Question about the Synthesis of alpha-methyltryptamine using tryptophan

    I have an Idea of a possible Synthesis route of aMT using tryptophan as the starting material. I have looked for a synthesis like this on this forum, but I have not found anything, so if a question like this already exists I am very sorry. The synthesis i thought of is starting with the...
  2. Rabidreject

    DMT and other tryptamine synth questions….please help…

    Okay so I have two syntheses of n,n-DMT and a rough idea of a synth for DET also. I have a couple of questions that I really need answering. I am not going to list the steps or anything, just the general gist of what happens in them or how they differ and why that confuses me. I have done the...
  3. Rabidreject

    PLEASE HELP! Water bath and rotovap questions…

    Hey guys, I have a synth coming up (currently waiting for the main reagent) and the synth calls for both a water bath and rotovap. So to put my situation into perspective it’s important to say that I am learning chemistry as a hobby and I do not make things for people other than myself! Okay...
  4. Alpino [ B.H.M.]

    Anyone who has tried this recipe ? [ 4-HO-DET ]

    Question 
    SYNTHESIS To a solution of 5.0 g 4-hydroxyindole in 20 mL pyridine there was added 10 mL acetic anhydride and the reaction heated on the steam bath for 10 min. The reaction was quenched by pouring over chipped ice to which was added an excess of NaHCO3. After being stirred for 0.5 h the...
  5. Rabidreject

    Have I FINALLY done it?

    So as I’m sure a few of you have gathered iv been trying the ketone catalysis of tryptophan to yield tryptamine but was having issues. turns out I just couldn’t follow instructions because I was taking breaks, not making notes and forgetting where I was. I’m pleased to say iv corrected these...
  6. M

    Bufotenin from Serotonin?

    Serotonin is a tryptamine, and so is bufotenin. The only difference between the two is that bufotenin has two methyl groups where the NH2 group should be: In theory could someone get a potent enough methylating agent to do this in one step? If this is possible, then it should also be possible...
  7. N

    Indole-3-yldiethylglyoxylamide reX

    Question 
    Hi, hope this is not a stupid question. Is IPA suitable for Indole-3-yldiethylglyoxylamide recrystallization? Checked the boiling point and it also seems suitable for removing excess diethylamine. Thanks in advance for your help.
  8. WillD

    DMT Synthesis From Indole (Experimental)

    Reagents: Indole (cas 120-72-9) 25.0 g, 211 mmol; Diethyl ether 700 mL; Oxalyl chloride (cas 79-37-8) 55.0 g, 433 mmol; Dimethylamine 1.94 mol in diethyl ether 20% wt/vol solution; Distilled water 1 l; LAH 1 M solution in THF 800 mL, 800 mmol; Sulfuric acid (H2SO4 100%) 21.3 mL, 400 mmol; THF...
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