Hey guys, I have some morphine galcial acetic acid and H2SO4.
Can somesone zell me how to make 6-mam wirht it?
Can somesone zell me how to make 6-mam wirht it?
6-monoacethlmorphine
- Thread starter RegulierTier
- Start date
Acetic acid isn't acylating agent, you should produce anhydride from it first.
Why 6-MAM? you do not have enough acid for two groups to make Heroin?
Why 6-MAM? you do not have enough acid for two groups to make Heroin?
- By RegulierTier
It's not about the quantity of educts, more about the quality of my products.
I don't want to acetylate both, 3rd and 6th position. To acetylate only the 6th position you need glacial acetic acid.
Acetic anhydride ist strong enough to acetylate both and create diamorphine but the 6-mam is much stronger than heroin.
I don't want to acetylate both, 3rd and 6th position. To acetylate only the 6th position you need glacial acetic acid.
Acetic anhydride ist strong enough to acetylate both and create diamorphine but the 6-mam is much stronger than heroin.
6-monoacetylmorphine is 30 times stronger than diacetylmorphine...
I think it's the same synthesis but with glacial acetic acid instead of acetic anhydride...
I think it's the same synthesis but with glacial acetic acid instead of acetic anhydride...
@RegulierTier, 30% stronger, not 30 times.
Where did you get this info? Don't believe everything that you read on Wikipedia if there are no links to reliable sources.
Where did you get this info? Don't believe everything that you read on Wikipedia if there are no links to reliable sources.
- By RegulierTier
Nevertheless i think it's a good idea to make directly 6-mam if you have pharmaceutical morphine, instead of making diamorphine... 
It's more potent and glacial acetic acid is easier to get your hands on, 'cause it's not a controlled or banned substance like acetic anhydride in most countrys.
It's more potent and glacial acetic acid is easier to get your hands on, 'cause it's not a controlled or banned substance like acetic anhydride in most countrys.
From my understanding glacial a.a. produces tar and to get white asia product use acetic anhydride..sodium sulfate in with the mix and heat with a water condenser on top for few hours. Should be info in this site literature. The aspirin synthesis is same also 5 drops concentrated sulferic acid to catalyze and start the reaction.the sulfite absorbs the water not wanted in reaction tho also H20 is byproduct. The hive and blue light has more info.