Question Acetoacetanilide to APAAN

[haze2000]

Do you guys think that the conversion of Acetoacetanilide [102-01-2] to APAAN [4468-48-8] is possible? I ask this because in a paper from 2018 there is mentioned that 102-01-2 was seized way back in 2013 in holland and that this can be readily converted to apaan. I will attach link and relevant text below.

[ In 2013 a pre-pre-precursor was discovered in the Netherlands 3-oxo-N-phenylbutanamide [102-01-2] which can be readily converted into APAAN ]

https://www.sciencedirect.com/science/article/abs/pii/S0379073818301166

 

[WalterFan]

Yes, if you start from 102-01-2, the most advanced way to make the final product takes 3 weeks

 

[lalalander]

Do you know anything about how exactly this can be done?

 

[yuiopjkl]

In the reference cited, 3-oxo-N-phenylbutanamide is not mentioned, but the substance that is mentioned is 3-oxo-2-phenylbutanamide (cas: 4433-77-6, alpha-phenylacetoacetamide)

 

[WalterFan]

Then why don’t you try it instead?