Best solvent for 4-MMC synth

[RegulierTier]

Whats the best solvent for making 4-MMC?
Benzene worked fine for me but I don't realy like to work with it.
DCM was a bit complicated. Nothing felt out after I gave HCl to it. Had to evaporate some DMC and cool it down.
Is toluene an option? What do you use?

 

[Jesse_Pinkman_]

E
ethylacetate

 

[Jesse_Pinkman_]

E
ethylacetate, short reaction time

 

[Berlin777]

This is the reason I like working with DCM:
Dichloromethane, commonly called methylene chloride, is a solvent that is widely used in chemical research and manufacturing. It is a highly volatile liquid (see fast facts table), but it is neither flammable nor explosive in air.

And it does not smell as strong as toluene

 

[Marvin "Popcorn" Sutton]

If bromination is involved, the following solvents are used
Glacial acetic acid, dichloromethane, benzene.
If your question concerns the amination reaction, the following substances are used
Toluene, dichloromethane, benzene.
If you notice, when performing bromination in dichloromethane and benzene, you may not extract 2b4mp and you may start the amination reaction.

 

[$!$]

THF DMSO NMP

 

[thezerocoke]

hey Guys , i know some people will think what a noob . but yes i am new to this but really interrested in learning , whats benzene ?

if i look for it , i find a lot of different types of cas for it.

thanks for helping out

 

[$!$]

dont use benzen is toxik

 

[thezerocoke]

Thank You for your answer, is it possible the use something like petrolium bezine cas 64742-49-0 ?

somebody told me that it also works and easy to get on .

is he talking BS ?

 

[TheVacuumGuy]

I don't think you should care too much about toxicity. Yes it has shown Benzene is "carcinogenic", given when working in it every day in and out. I wonder why people are talking toxicity and shit while they're mixing all kind of hefty materials to making fucking drugs .

Adding some wisdom to this post: