Amphetamine sulfate is a stimulant drug that is commonly used to treat attention deficit hyperactivity disorder (ADHD). It is a Schedule II controlled substance in the United States and is illegal to manufacture, possess, or distribute without a valid prescription. Amphetamine sulfate is usually found in the form of a white powder that with a faint peculiar smell is usually snorted, swallowed, or injected. Amphetamine sulphate also can be sold as paste, which is polluted by additives and solvents to increase seller benefit. We are going to talk about pure amphetamine sulphate product and timings for its 100 g producing batch.
Approaches for Producing Amphetamine Sulfate
To produce amphetamine sulfate, the raw materials must first be acquired. This includes the chemical ingredients that are used to make the drug. The exact ingredients vary depending on the recipe and method used. There are two the most popular amphetamine synthesis approaches:
1. P2NP reduction by aluminum amalgam
2. P2NP reduction by NaBH4.
Once the ingredients have been acquired, they must be processed into a usable form. This can include purifying, distilling, or otherwise manipulating the ingredients to create the desired product. P2NP can be easily recrystalized and dried by follofing manual for about 3-5 h. The next step is to combine the ingredients in the correct proportions. This process is typically done in a laboratory setting and requires precise measurements.
1. P2NP reduction by aluminum amalgam
2. P2NP reduction by NaBH4.
Once the ingredients have been acquired, they must be processed into a usable form. This can include purifying, distilling, or otherwise manipulating the ingredients to create the desired product. P2NP can be easily recrystalized and dried by follofing manual for about 3-5 h. The next step is to combine the ingredients in the correct proportions. This process is typically done in a laboratory setting and requires precise measurements.
P2NP Reduction Via Aluminum Amalgam Synthesis Way
First of all, aluminum amalgam has to be prepared. It takes about 30 min for cutting Al foil, its weighting and Al amalgamation. Reaction is carried out in 3 flasks 10L. During this time, you can prepare NaOH aq solution. Complete reduction reaction takes about ~1 h with reaction load about 50 g / each flask (150 g total) of P2NP (to yield ~100g amphetamine sulphate). Reaction mixture alkylation and following amphetamine free base oil extraction procedure takes about ~1 h. The solvent is dried over desiccant, filtred and evaporated for ~1h. Next, acidification of amphetamine free base acetone solution have to be done. This procedure takes about 1h and ~30 min for precipitation and filtration.
Total shortest reaction batch takes approximately ~ 5 h.
P2NP Reduction Via NaBH4
Reaction is started from NaBH4 decent amount desolation in dry IPA ~30 min. Then, 150 g P2NP is slowly added for approximately 4-5 h. CuCl2 solution addition and heating at 80 °C takes ~1.5 h. Cuprum sediment filtration, alkalization and layer separation need about 1h and addition ~30 min for amphetamine freebase extraction from sludge. Acidification and filtration procedure take approximately the same time as in previous synthesis way ~2 h.
Total shortest reaction batch takes approximately ~ 9.5 h.
Similar vacuum drying procedure takes about 48 h for both approaches. It is important to highlight that you can start next synthesis batch during this drying exposure in a vacuum desiccator until constant dry mass of amphetamine sulphate powder.
Time Required to Produce 100 g of Amphetamine Sulfate
As you can see, synthesis time is not significantly different in both approaches. Synthesis can be separated for three full working days. The biggest synthesis time part is a passive vacuum drying, which isn't takes chemist presence. The amount of time required to produce 100 g of amphetamine sulfate depends on the method used and the skill level of the person performing the process. For an experienced chemist, the process may take several hours to complete. For a novice, the process may take significantly longer due to the complexity of the process and the need for precise measurements. Additionally, if the ingredients are not of good quality or if the process is done incorrectly, the time required to produce the desired product may be significantly longer.
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