most feasible plant for safrole extraction

[mithyl2]

which widely available/legal plant is best for safrole extraction?

what would be the best way of extracting the safrole from the plant material?

 

[Osmosis Vanderwaal]

What's your very general geographic location? Where I'm at. For instance , Sassifrass albilum is very common. It's free and Abundant and loaded with saffrole as much as 75mg/g! Star anise camphor trees, peppercorns gingerand several other plants contain it then there are plants that contain precursors like euginol or myristacin? It can be synthesized also

 

[mithyl2]

uk. i think it's very limited.. perhaps i could plant something though, but the climate here is generally cold, especially now

 

[Osmosis Vanderwaal]

I've seen posts where people have got a fair amount of material from whole peppercorns, but let me check a couple of places real quick and I'll link you

 

[Osmosis Vanderwaal]

The first 102 documents here are reLated to saffrole or mda/mdma. That'll give you some ideas. Keep in mind it's 15 years old or something

Rhodium: Drug Chemistry Archive

 

[mithyl2]

thanks. i've seen that before but haven't managed to comb through all of it lol.

i did know about the peppercorns but heard that the yield was terrible. after looking the yield seems to be 10% at best, but also seems easy enough to extract.

for anyone else interested i think is the relevant page:

safrole from plants

 

[testint]

In the us you can buy sassafras essential oil this method is kind of out of date many others much better

PMK glycidate
P2nP

 

[mithyl2]

that's surprising because i though it had been shut down hard in the US. even so i'm in uk.

i think i can synthesize pmk but would still like to have some options for alternative precursors.

 

[testint]

PMK

52190-28-0 - 2-Bromo-3',4'-(methylenedioxy)propiophenone - brown powder
28578-16-7 - PMK ethyl glycidate - Yellow powder or white powder or reddish liquid, you can choose
13605-48-6 - 3-(1,3-Benzodioxol-5-yl)-2-methyl-2-oxiranecarboxylic acid methyl ester - white crystal
1823274-68-5 - 3,4-Methylenedioxy-N-benzylcathinone (hydrochloride) - brown chunk solid
1314093-06-5 - white powder

BMK
20320-59-6 - Diethyl(phenylacetyl)malonate - dark brown liquid
5449-12-7 - 2-methyl-3-phenyl-oxirane-2-carboxylic acid - white powder
5413-05-8 - Ethyl 3-oxo-4-phenylbutanoate - light-yellow liquid
80532-66-7 - methyl-2-methyl-3-phenylglycidate - white powder
718-08-1 - Ethyl 3-oxo-4-phenylbutanoate - colourless liquid
16648-44-5 - Methyl 2-phenylacetoacetate - white powder

The plant sources are to many to list

 

[mithyl2]

the problem is i think all of those are watched chemcials. i'm looking into a scalable synthesis to MDP2P from ethyl vanilliin

 

[testint]

P2NP is available on ebay or was the vanillin route is proven but scaleable? Large batches are almost impossible without a connection to watched precursors not to mention the huge volume of solvents that will flag you even with a legal route I don't mean to be a downer but most civilians are stuck with low scale

 

[mithyl2]

i'm sure there are definitely ways to scale up into large scale with what is available to civilians, especially due to china.

a big problem with the vanillin route is that the first step requires heating a lot of the sulfuric acid with the vanillin. heating lots of sulfuric acid in batch reactors doesn't sound good :/

 

[testint]

What about your solvents ? 1000's of liters .. or even just 100's

 

[mithyl2]

could make fake companies to take delivery of solvents. it would be a big operation and require lots of capital and a good head for logistics

 

[testint]

Didn't say it was impossible just out of most peoples reach

 

[2-79-790125]

Up for consideration .....Illicium Parviflorum "Florida Sunshine"