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Question Some questions about Synthesis of anesthetics

lain

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I tried to modify caffeine to make it anesthetic, can this reaction work? Has any chemist tried it?
 

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Osmosis Vanderwaal

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Everything I read says not a snowballs chance in hell. Sodium is not a catalyst its a strong oxidizer reducer, thatnwouldmprobably explodemor at least destroy the entire molecule br² cant be added in this way. Br² alone wouldn't react all all because the aromaticity of caffiene is high and nitrogens stabilize the molecule even more. That's just Speculation
 

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Thank you. I'm going to catalyze it with iron bromide instead of sodium
 

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I can replace liquid bromine with hydrogen bromide
 

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Can I activate nitrogen with hydrogen ions? So I can attack with alkali
 
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