Cocaine Synthesis from Tropinone

[Osmosis Vanderwaal]

The CHINESE will sell you 2-cmt, which is only a couple Reactions away. I got a price quote from them but I couldn't afford it based on my fear that I couldn't pull it off. They quoted me $150 for a 10g sample. So you are probably looking at...idk, $10,000 kg?
I know it works because about 1 out of 200 samples tested by drugs-data, where you mail it in and pay $100, is synthetic cocaine.

2-Carbomethoxytropinone - Wikipedia

en.m.wikipedia.org

 

[Germanium]

If I want to synthesize from 2 cmt, what is the procedure?
Any examples would be helpful...

 

[Osmosis Vanderwaal]

I wrote about it, either above or in another thread about this topic. An alkylation reaction (methylation) and a Fischer esterfication are the 2 reactions. You can find examples in pretty much every cocaine synthesis scheme. I wouldn't suggest one over another based on I haven't done it.

 

[Germanium]

Okay. Thanks!
I will search more and read past posts.

 

[OmID]

Hi everyone
I'm going to synthesis cocaine from tropinone and I will share the pictures and videos on this site.
I'm a bit noob and this is my second synthesize.
I have few questions:
1; tropinone is not solves in ether but how received unredacted tropinone of it?
2; turn 2 cmt into ecgonine
At first I'm have in mind use nagh amalgam but it's sund nabh is way easier
But I can't find any data on internet
3; I make nagh amalgam and have no idea for Purification of it
4; at the end how to split racemic cocaine and cocaine
At the end I'm apologize for my poor English knowledge and any help even a Link or short sentence could be useful

 

[Osmosis Vanderwaal]

I can link you to the documents that answer these questions but I can't elaborate on them. This is a lofty goal for a second synthesis. I've read that the enantiomers of cocaine also have some cns activity so I'm not sure that you have to seperate them.

 

[OmID]

By doing this, you are doing me a great favor

 

[OmID]

i added 3.48 g tropinone 1.38 g nametoxid in to a fbf 50 ml flask and pur a mixture containing a 4ml dimethyl carbonat and 10ml toluene.
Now I'm waiting for any color change

 

[The-Hive]

Any update on this

 

[OmID]

After reflux I bring the temperature to 0
Ad 2.5 g nhcl4 15 ml water mixture extract whit chloroform (50) ml and put into Separatory funnel and wash the rbf whit chloroform 50 ml
Al solvents mix to separatory funnel shake 3 times 3m
And extract 2 times more whit 50 ml
And I extract 2 times more for better results
I get a cloudy solution and dried
Now I'm going to vacuum distillate chloroform

 

[9-Tryptophan]

Did you get something out after vacuum Destillation?

 

[OmID]

Yes I get a yellow to Brown oil
And at the end
This synthesis was not interesting to the members, so I stopped posting the steps to the forum

 

[The-Hive]

Looks so simple but we all know it’s not. They are several discussions on this synthesis on the forum. someone was saying you’ll be lucky to get 5%.

 

[OmID]

My motivation in this synthesis is not money, dear friend I can access the product at half the price of tropinone If I reach even 1%, it is a victory for me If I don't get any results, at least I enjoyed the journey

 

[The-Hive]

I wasn’t being negative towards what you were doing . It would be amazing to see this synthesis