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I think something wrong with graph.
If you use L+-tartaric acid(cheaper and easier to find)the D enantiomer(amph,Meth) will be in the solution not in the solid as there appears.
If you use D-tartaric acid(more expensive and difficult to find) the D enantiomer(amph,Meth) will be in the solid.
Thanks.
If you use L+-tartaric acid(cheaper and easier to find)the D enantiomer(amph,Meth) will be in the solution not in the solid as there appears.
If you use D-tartaric acid(more expensive and difficult to find) the D enantiomer(amph,Meth) will be in the solid.
Thanks.
G.Patton
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His scheme is correct. Salt is precipitated into the solid state. No difference, d-amphetamine l-tartaric acid salt or l-amphetamine d-tartaric salt. You can change acid and get difference isomer in the solid state with following procedures.
P.S. same for methamphetamine.
P.S. same for methamphetamine.
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What do you mean under pic 18.
"We precipitate d-amphetamine with an additional amount of d-tartaric acid". I thought the d tartaric acid you used crashed the l amphetamine d tartaric salt out. How is it going to precipitate the d amphetamine left in the solution?
"We precipitate d-amphetamine with an additional amount of d-tartaric acid". I thought the d tartaric acid you used crashed the l amphetamine d tartaric salt out. How is it going to precipitate the d amphetamine left in the solution?
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D-tartric leaves the desired enantiomer in solution, your solid is now your waste in this case, opposite for L-tartaric (the common one), you then precipitate with your desired acid. During both these processes you will arrive at the sulphate or phosphate, as the tartrates are not storeable
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I understand that. But if you read the procedure that is posted , here it is.
"Extract with 5 ml of petroleum ether and warm the solution, add 2.45 g of d-tartaric acid in alcohol solution to the mixture. Then add alcohol until completely dissolved and cool with stirring. The l-amphetamine d-tartaric salt precipitates. The d-amphetamine remains in the solution. You can repeat procedure of cleaning precipitate of l-amphetamine d-tartaric salt by methanol to increase yield."
This next bit i am talking about .
"We precipitate d-amphetamine with an additional amount of d-tartaric acid. We filter the precipitate, get the base of d-amphetamine, adding alkali to pH = 11"
"Extract with 5 ml of petroleum ether and warm the solution, add 2.45 g of d-tartaric acid in alcohol solution to the mixture. Then add alcohol until completely dissolved and cool with stirring. The l-amphetamine d-tartaric salt precipitates. The d-amphetamine remains in the solution. You can repeat procedure of cleaning precipitate of l-amphetamine d-tartaric salt by methanol to increase yield."
This next bit i am talking about .
"We precipitate d-amphetamine with an additional amount of d-tartaric acid. We filter the precipitate, get the base of d-amphetamine, adding alkali to pH = 11"
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Ye it doesnt make sense , wait and see what the video is like he is making
G.Patton
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Ok. But how can you precipitate d amphetamine with d tartaric acid, When you seperated
l amphetamine d tartate with this same tartraic acid in the step before
l amphetamine d tartate with this same tartraic acid in the step before
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There is alot of confusion around this topic. Hopefully your video sheds some light on it .
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