One-pot Amphetamine Synthesis From P2NP With NaBH4/CuCl2 (1kg scale)

aa1178251182

Don't buy from me
Resident
Joined
Dec 27, 2022
Messages
37
Reaction score
6
Points
8
No idea what went wrong, no testing equipment. The resulting amphetamine phosphate has no effect at all.
 
View previous replies…

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,663
Solutions
3
Reaction score
2,738
Points
113
Deals
1
Check its melting point. Also, how much have you sniffed?
 
View previous replies…

aa1178251182

Don't buy from me
Resident
Joined
Dec 27, 2022
Messages
37
Reaction score
6
Points
8
I don't know how to use it. I swallowed 0.5g and inhaled a bit through my nose, nothing works
 

Hank Schrader

Don't buy from me
Resident
Joined
Nov 10, 2022
Messages
79
Reaction score
165
Points
33
Make sure you have phenylnitropropene and not nitrostyrene. Perhaps you were sold an analogue, and you received phenylethylamine.
 
View previous replies…

aa1178251182

Don't buy from me
Resident
Joined
Dec 27, 2022
Messages
37
Reaction score
6
Points
8
I request to purchase CAS705-60-2. I bought two barrels, which have changed color after being stored for a long time, and the discolored raw materials were recrystallized with absolute ethanol to restore their original appearance. The merchant clearly stated that they are CAS705-60-2. I experimented with LAH and got the same product that didn't work. I don't know where the problem is.
 

Hank Schrader

Don't buy from me
Resident
Joined
Nov 10, 2022
Messages
79
Reaction score
165
Points
33
Most likely you are dealing with nitrostyrene, which is obtained from nitromethane with benzaldehyde. This often happens in the precursor market. Also, due to the problem of getting nitroethane, often styrene is mixed in and you end up with a mixture of amphetamine and phenylethylamine.
 

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,663
Solutions
3
Reaction score
2,738
Points
113
Deals
1
As I told you before, you can check the melting point of your reagent and product and you'll figure out was it p2np or nitrostyrene as Hank said.
 

KokosDreams

Don't buy from me
Resident
Joined
Aug 16, 2022
Messages
912
Solutions
2
Reaction score
595
Points
93
After evaporating the IPA off the freebas/IPA solution, the compound has turned into a thicker mass than expected when we removed it from the rotovap (picture attached).

Our plan was to do a steam distillation (1:1 water ratio) and two DCM extractions after.

Unfortunately, after combining the extracted aeqeous layer with the organic layer + filtering + drying both, the bottom of the flask has turned into a gele like it happened to many others on this forum after letting it rest over night at around 7-9 °C.
Our assumption to this is that either the drying agent Sodium sulphate or leftover sodium hydroxide from the NaOH solution has remained in the solution throughout the filtering process which now caused the oil to become thicker than expected after evaporating the IPA.

My question is, should we still continue with a steam distillation + dcm extraction now?
Or are there other options to reclaim the fluid state of the freebase?

Cincerly,

Koko
 

Attachments

  • eRPpidAmTs.jpg
    eRPpidAmTs.jpg
    1.8 MB · Views: 256
  • JS5pH2lIcf.jpg
    JS5pH2lIcf.jpg
    1.9 MB · Views: 250

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
678
Reaction score
510
Points
63
Deals
5
What did you use to dry? Calcium salt i’m guessing?
@KokosDreams

ah sodium sulphate, I’m blind.Did you buy it anhydrous or dry yourself?
Mass gells up with calcium salts or in combination with water mostly (freebase + water = gel)
 

KokosDreams

Don't buy from me
Resident
Joined
Aug 16, 2022
Messages
912
Solutions
2
Reaction score
595
Points
93
We bought it anhydrous.

After a few chats with some people here we have now decided to prepare a 10ml sample from the compound and mix it with 100ml of d2h2O to then extract it with 16ml DCM.
Attached you can see the compound + water solution aswell as how it looked after adding dcm.

The experiment would now be to prepare another 10ml sample of the compound, carry out a steam distillation + dcm extraction to see if we can get the result to crystalize with acetone, methanol and sulphuric acid

I will also attach a picture of another sample I put aside from the organic & aeqeous layer
 

Attachments

  • lU96uMqhgD.jpg
    lU96uMqhgD.jpg
    1.9 MB · Views: 303
  • T4hzwyq75P.jpg
    T4hzwyq75P.jpg
    1.9 MB · Views: 272
  • d5VTqOUeja.jpg
    d5VTqOUeja.jpg
    1.8 MB · Views: 248

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
678
Reaction score
510
Points
63
Deals
5
Oh I see now , I would just distill that, it's just an emulsion, this is how it's gonna come over in your dean stark or wherver you are collecting first few ml till steam picks up.Also you're way off on the ratios, it will take like a whole liter of agua to distill over MAYBE 100 of base depending on steam temp, source of steam etc.
I suggest external source of steam, maybe immersion heater in a flask + heating of the base container.
 

Stretcher5335

Don't buy from me
Resident
Joined
Dec 20, 2022
Messages
16
Reaction score
9
Points
3
Fellas is it possible to run this with NaBH3CN? Thank you
 

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,663
Solutions
3
Reaction score
2,738
Points
113
Deals
1
This substance extremely poisonous
 

blackburn

Don't buy from me
Resident
Joined
Aug 18, 2022
Messages
103
Reaction score
48
Points
28
Hello
after the batch 1kg p2np we have about 10l of diluted ipa/amphetamine, why do we have to add more ipa/acetone to this before we drip in sulfuric acid when there is already enough ipa in it.

when we have pure amphetamine base, we dilute this with amf/ipa 1:2 or 1:3 before adding sulfuric acid...

and is it possible to run the synth with methanol/h20 instead of ipa..

Thanks :)
 

Melv99

Don't buy from me
Resident
Language
🇺🇸
Joined
Jan 16, 2023
Messages
31
Reaction score
11
Points
8
Wondering this myself. Unless I'm mistaken or missing something.. We evap IPA to leave FB then add IPA/Acetone. Can't we go straight to Acetone/Sulfuric since it's already in IPA?
 

blackburn

Don't buy from me
Resident
Joined
Aug 18, 2022
Messages
103
Reaction score
48
Points
28
yes, it is fine to add sulfuric acid directly to the ipa/amf base, it was a mistake on my part, I thought they added ipa and acetone, acetone is to clean the product I guess, but it works well without acetone included.
 

UWe9o12jkied91d

Don't buy from me
Resident
Joined
Aug 8, 2022
Messages
678
Reaction score
510
Points
63
Deals
5
You can add conc. sulphuric but its always a good idea to dillute it with some acetone.Dropping it in conc. leads to local over-acidification, where regardless of basic medium a portion of your product will be irreversibly destroyed.
 

Melv99

Don't buy from me
Resident
Language
🇺🇸
Joined
Jan 16, 2023
Messages
31
Reaction score
11
Points
8
In the video it says Acetone is added to the Ipa/base solution. I don't see the Ipa being evaporated off. If it possible to do without the evap step?
 

G.Patton

Expert
Joined
Jul 5, 2021
Messages
2,663
Solutions
3
Reaction score
2,738
Points
113
Deals
1
Yes. You can. The difference in crystallization procedure. It will be a little bit longer.
 
Top