The table shows the density of 40% methylamine as 0.89g/ cm3, hence 7.18g of pure methylamine gas is obtained in 20ml.
Let us compare the molecular weights of methylamine and its hydrochloride:
M (CH3NH2)HCl = 67.518 g/mol
M CH3NH2 = 31.057 g/mol.
Ratio = 2.174
If you use the proportions from the synthesis, you will need 15.6g of methylamine hydrochloride to replace 20ml of 40% methylamine solution.
Methylamine hydrochloride needs to be dissolved beforehand in the proportion of 1g to 2.5ml water (15.6g and 39ml).
Prepare sodium hydroxide (NaOH) solution of 18g and 54ml water, let it cool and pour it into a flask with 2-bromo-3,4-methylenedioxypropiophenone solution. After that, add methylamine hydrochloride solution. Then continue according to the instructions.
Let us compare the molecular weights of methylamine and its hydrochloride:
M (CH3NH2)HCl = 67.518 g/mol
M CH3NH2 = 31.057 g/mol.
Ratio = 2.174
If you use the proportions from the synthesis, you will need 15.6g of methylamine hydrochloride to replace 20ml of 40% methylamine solution.
Methylamine hydrochloride needs to be dissolved beforehand in the proportion of 1g to 2.5ml water (15.6g and 39ml).
Prepare sodium hydroxide (NaOH) solution of 18g and 54ml water, let it cool and pour it into a flask with 2-bromo-3,4-methylenedioxypropiophenone solution. After that, add methylamine hydrochloride solution. Then continue according to the instructions.
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