5-minute Methcathinone synthesis (from pseudoephedrine)

[BHBlueberry]

We just need one pack of sudafed 720mg pseudoephedrine (or local equivalent) and 350mg KMnO4.

We take out the pills, put them between two paper sheets and destroy them with the hammer to dust (red shield too).

We pour about 80ml of warm water into the glass (not cold but not hot like from the pot), add our powder and stir it until all bigger parts are liquified. Now we sip KMnO4 between the same two sheets of paper and we mill it to dust also. We add our dust to our mixture, stir it once upon a time until all the KMnO4 redness (sorry if you are daltonist) disappear and we will have only water mixed with coffe-alike fumes. So now we take the paper-towel (not any handcuffs or tp!!!) we make it to 1/4 size and 4x thick square, nap it with a little cold water and put it on other glass. Now we gently pure our mixture on the towel - it will filter out naturally (we squeeze the rest being amazed how papertowels are not breaking like tp and ch would). All the diamond-clear liquid is our product and all the firty fumes should stay at the towel. For me there is no better ketone than Methcathinone

 

[G.Patton]

Have you checked your cathinone by Drugs testing reagents? Reaction product has dark brown color? Can you show pics of this method or synthesized product, if it is possible?

 

[BHBlueberry]

I could show you everything but there is not much to see there The methcathinone (ephedrone) is very popular in our country.

The product is crystal clear liquid - the brown coffe-alike stuff you reject.

Here you have video of making it for shots (longer time):

Obtaining ephedrone (methcathinone)

Obtaining ephedrone-otherwise the reaction of oxidation of pseudoephedrine with potassium permanganate. pseudoephedrine extracted from the drug Sudafed. reaction made cold with vinegar. the envelopes can be even more precisely ...

hyperreal.tube

 

[krtl91]

hı bro. thx for information. ı want to ask that after we get the clear liquid as our product , can we evaporate the liquid and have it in crystal (powder) form ? thank you.

 

[Putin's Daddy]

One little question. From where do i get KMnO4?

 

[Loooow]

Methcathinone is a fine thing if it is clean.For a chilled out party better than all the wannabe MDMA that is available everywhere!!!!

 

[MadHatter]

KMnO4 is often sold as a water purification chemical. Have you tried this new thing called ... Google? It's available on Amazon, Ebay, a lot of online vendors selling water filters, some plumbing stores etc. Can't give you exact instructions without knowing where you live.

 

[Putin's Daddy]

thanks man. do u also know how to crystelize the solution?

 

[G.Patton]

Problem that methcathinone (ephedrone) almost insoluble in water. If you get free base ephedrone, it has to look as layer, which is insoluble in water. Also, there is no any acids to make salt with this free base (in this reaction).

Water Solubility

2.22 mg/mL

 

[BHBlueberry]

translation via google from pl:

Place the funnel on a clean jar with 3 coffee filters in it. Filter by carefully pouring the methylcathinone solution through the filter. Take care that brown sludge remains at the bottom - it ends up in the filter last to prevent clogging of the filter. The solution after filtration must be completely clean, clear, otherwise it will be necessary to filter again.
Then you need to correct the pH value. Measure it with litmus papers, the ph will then be around 8-9. You must introduce hydrochloric acid to be sure that the HCL salt of methylcathinone is formed. Add acid slowly, drop by drop, while stirring the solution with a baguette. Check the pH value after each added drop of hydrochloric acid. The correct pH value is 8-9. This should be done after adding about 3-4 krolpa.

NOTE: you must be careful not to add too much acid as this may lead to some problems in the following steps.

7. Crystallization

Pour the entire contents of the jar into a Pyrex vessel (pyrex is necessary) and then put the vessel on the stove to heat it. Start to heat the whole thing on as low a fire as possible, taking care that the liquid during this activity (5-7 hours) does not start to boil even once. The temperature should be between 70-80 * C.

CAUTION:
0 h temp. 25 * C / 760ml
2 hours. temp. 75 * C / 550ml
4 hours temp 75 * C / 300ml
6 hours temp 75 * C / 150ml
8 hours temp 75 * C / 10ml

When most of the water has evaporated and only approx. 10 ml is left, the liquid should take a slightly yellowish and very oily form. It is important to evaporate as much water as possible, otherwise it will hinder crystallization.
Add about 20 ml of methanol to the liquid remaining in the vessel. At this point, you should notice the formation of the first white and yellow crystals.
Stir gently with the baguette, then separate the alcohol by pouring it into a clean container or jar.

NOTE: Methanol helps to get rid of water and dry the crystals in a certain amount of time.

The oily liquid in the pyrex vessel slowly begins to disappear, more and more crystals are formed. On the smallest flame with constant stirring. The crystals will become dry and stable. BE CAREFUL not to overheat !!!
In the event that the crystals discolor (green-blue color) or begin to melt - be sure to reduce the temperature.
Then pour 20ml of acetone into the pyrex vessel. You will immediately notice that the crystals will turn an almost snow-white color, and the negligible amounts of dirt (coffee filter pieces, hair, etc.) will remain in the acetone.

NOTE: Acetone helps get rid of impurities and oily residues.

Separate the acetone and pour it into the vessel where you previously added methanol. You will immediately notice a certain amount of crystals in this vessel, recovering and saving them. Continue the evaporation until there is no more liquid in the vessel or the crystals are a dry powder. For example, use a knife to remove the crystals from a vessel containing a mixture of methanol and acetone. With a razor blade, you can crush them even more into a powder.

NOTE: you should get more than 3 grams of methcathinone, as KmnO4 is combined with hydrochloric acid to form a by-product, potassium chloride, which eventually crystallizes with metal.

8. Product testing

a.) Burning: Flame a small amount of powder in a spoon. The powder will begin to melt first, then it will boil and finally ignite with small flames. There is a small black residue left on the spoon.

b.) Taste: very bitter

c.) Appearance: White or white-yellow crystals. When ground, they turn into a powder with a consistency similar to powdered sugar or flour.

Odor: Typical of ketones

 

[G.Patton]

With all my respect, this method is bullshit. You won't get Methcathinone in water solution cuz it isn't soluble. I think it something else.

 

[MadHatter]

Not even the hydrochloride salt?

 

[G.Patton]

You can't extract ephedrine free base from pills by water. You can get mixture or E*HCl with fillers, which will not react with KMnO4.

 

[MadHatter]

Sorry, I'm not sure which part of this post you criticize. Is it the original synth description or the part about the crystallization?
Because I found the source of the latter part: it's Erowid. And in it, the ephedrone workup is done in IPA or acetone. You can find it here:

Erowid Cathinone Vault : Methcathinone FAQ

Frequently Asked Questions about methcathinone.

erowid.org

The part that is pasted in this thread doesn't make that clear.

 

[alwaysalpha]

Thanks man i wqs looking for this for a long time

Do you have any advice for me ?

 

[G.Patton]

This method looks real, but I think the yield is extremely low. In my opinion, the best way to provide reaction E free base with KMnO4 in polar solvent.
I want to say that water extraction gives E*HCl salt. In described method author said that final solution of water contains cathinone salt, It is impossible or there are only traces of product.

 

[MadHatter]

Ah, ok, I see. You mean the original text. Yes, that would make any ephedrone produced end up in the filter, wouldn't it?

 

[G.Patton]

E*HCl won't react so fast in water solution

 

[8n398k20k280]

so in the end is there a synthesis or not?

 

[MadHatter]

In the video he forces the nonsolids through the cotton filter in the syringe, that might push any freebase methcathinone into the final solution. If there is any.

But then there's the issue of over-oxidation by the potassium permanganate. I don't know if dichromates would cause the same problem, but since they're nasty as f*** I would never use them anyway.
In the Erowid synth description the over-oxidation is minimized by chilling the starting material and carefully minimizing the amount of permanganate being used. Do you think this would work?
Seems like the reasonable modifications to this synth would be:
1. Start with ephedrine freebase
2. Use IPA for a solvent, not water
3. Use a minimal amount of permanganate
4. Add acid to any ephedrone freebase produced, to precipitate stable salt.

 

[betaketolove]

The reaction works because vinegar will transform that base to salt, acetic mcat.. I tried it, it works.. it produces a very oily mixture of salt and whatever other shit (I tried it diluted at room temp). The salt is unstable, and will degrade quickly, never tried IV, never will
My point is it works, but I had access to pretty pure ephedrine (salt was the only impurity) .. Never tried with pseudo from pills, at least not yet
So, maybe hcl and checking ph every now and then during the refrigeration/diluted reaction and lots of alcohol and acetone may yield crystals..
I will try this when I have the money to throw out the window (or maybe not), but I think the cold reaction with some ph correction and not 12 hours of it, diluted with isopropanol and cleared with further acetone washes and alcohols may yiled crystals.. I will try the slow crystal route from water/iso
It works, but it's acetate..