One-pot Amphetamine Synthesis From P2NP With NaBH4/CuCl2 (1kg scale)
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I guess I'm stupid too ... that's what extraction is about to transfer from one phase to another. in this case, from the water phase to the nonpolar solvent phase. that's why IPA extraction is not done here because ipa mixes with water and only gives us a dilution of the solution ... is it wrong?
Then you extract the "freebase" from the water phase and you don`t extract the water phase. This was illogical .
IPA was evaporated in the instructions and oil comes out. Oil with water, I think.
Why you use IPA in the instructions @William Dampier?
IPA was evaporated in the instructions and oil comes out. Oil with water, I think.
Why you use IPA in the instructions @William Dampier?
Yes, it may well be, I was or am still a bit confused, but "to extract" has the meaning of to pull something out, to get something out or to take something out. But also in the recipes it is misleading that the aqueous phase is extracted, I unfortunately do not know the exact English term and how it is used.
If I draw the comparison to the Al/Hg variant, where we also extract the freebase after the addition of alkali, IPA is also contained in the aqueous layer, but here we dry over MgSO4 in the freezer and use petroleum ether for extraction., which we evaporate later. It is possible that the procedure is different due to the high scaling, because the steps only pay off on a laboratory scale. Perhaps the experts could answer this question for us. But if no drying should take place here, one has to register a loss in the yield by the contained water in any case.
If I draw the comparison to the Al/Hg variant, where we also extract the freebase after the addition of alkali, IPA is also contained in the aqueous layer, but here we dry over MgSO4 in the freezer and use petroleum ether for extraction., which we evaporate later. It is possible that the procedure is different due to the high scaling, because the steps only pay off on a laboratory scale. Perhaps the experts could answer this question for us. But if no drying should take place here, one has to register a loss in the yield by the contained water in any case.
whats up . I ran a little test today. on 25g p2e.g. I gently raised the value of CuCl2 and temp by 2 degrees during reflux .. I got such a beautiful oil. unfortunately I didn't have the distiller with me and the tests were done in the field. I think it is enough to wipe it a little more and it will be perfect. big performance seems. delicate but distinctive fragrance
I have one more question, will the cascade absorption consisting of a buffer and two Dreschl washers filled with a 10% alkali solution be able to eliminate the smell emitted during the reaction? everything, of course, connected to the radiator in advance. the diagram is supposed to look something like this. blue hose leading from the cooler to the buffer connected to the nipple. then it goes to a buchner flask in which there is a 10% alkali solution, the side outlet of the flask is connected to a hose which is introduced to the other such flask with the same solution, and finally a hose is mounted which connects to the carbon filter and the fan.
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It all seems very cumbersome.
Perhaps it would be simpler a system with a powerful extractor, carbon filter and, if possible, between ozone to purify the outlet air and come out clean without odors.
after adding 25% NaOh solution, phase separation, I added 1/3 dcm of the volume of aqueous solution. my question at what temperature should I distill? in my opinion, apart from freebase, there is still water in this solution, IPA and dcm, am I right? then distillation at Ok 83 degrees?the solution starts to boil somewhere around 50 degrees, to what temperature should it be raised?