P2P synthesis from BMK glycidate ethers

[Saul]

this is the preparation of P2P Phenylacetone CAS 103-79-7 made use of BMK Glycidic Acid ( sodium salt ) CAS 5449-12-7 with main ingredient sulfonic acid strength is 75% CAS 7664-38-2
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we are going to prepare 1 kg of BMK
take a 5 liter double neck flask
add 500ml boiling water . start with the mixer.
now slowly add 1kg of BMK salt. then add 1 liter of sulfonic acid. now connect the reflux and heat the contents of the flask to max temperature. plus minus 130°c. use a powerful mixer
Let it boil in reflux for 4 hours.
take the top layer and pour it into a measuring cup.
let the bottom layer cool and save for next time. ( we have no chemical waste for this preparation method )

now boil 1 liter of water and add it to the measuring cup. use a hand mixer to mix everything.
After mixing for a few minutes, let the measuring cup cool to room temperature.
remove the top white layer (this is water and waste that we don't need)
the bottom layer is P2P purified and ready to use.

ps: in this preparation we don't have to worry about water remaining in our P2P because water weighs less than P2P

ps2: if you keep these ratios, the P2P will have a ph value of 4 .
if you use more sulfonic acid the ph value will drop to 1. Therefore it is not necessary to use too much sulfonic acid.

 

[w2x3f5]

I tried your version of the synthesis, but did not use water, the synthesis takes place in microwave irradiation. At a certain moment, the temperature dropped sharply from 110 degrees to 50 degrees, the reaction was still violent. Have you noticed a drop in temperature as carbon dioxide emission starts?

 

[cernalit0000]

good evening a 1k bmk 5449-12-7 question. Relise with 1k phosphoric. Lower to ph 3 purified.
at the end rindios. 200g powder is normal or in q fail??

 

[w2x3f5]

You can write to me in English in private messages

 

[G.Patton]

Do you use H3PO4 cons or diluted solution? Thank you for your feedback.

 

[cernalit0000]

Good evening performs the synthesis
Use 1k bmk 5449-12-7
2 liters of water. 200g of soda
Allow 1 hour to dissolve 70g add 1k phosphoric. For 2 hours more
800g p2p. Then purify with water. Gave me 750 ml.
I reacted. Released 500 ml for distillation. And in the distiller
It gave me 200 thousand to tie with tartaric. Little final yield. 100g in q falleee????

 

[G.Patton]

Hola, amigo. English please.

 

[w2x3f5]

Try hydrolysis in pure phosphoric acid in the microwave. I got a yield of 80% percent of the theoretical, p2p of good quality, the meth turned out to be excellent, now I am optimizing the synthesis of p2p on sodium borohydride.
Later I will publish the result of repeated synthesis in the microwave, it is important to obtain a stable repeating synthesis result.

 

[mithyl2]

thanks for letting us know. what's the best way to get pure phosphoric acid? it's a solid isn't it?

 

[Win Win]

I want to ask if this recipe works.

 

[G.Patton]

Hello, I don't know. You didn't describe your way clearly. I can't answer you. I can't read your mind, man. You can write me in DM with your issue in order to avoid flood under this topic,

 

[chef learner]

If I use BMK to make P2P, what method should I use to make methamphetamine in the second stage?

 

[Johnson212]

If I have bmk sodium salt, should I start directly at the HCL hydrolysis step?

 

[Throw-off]

Yes. READ the whole thread it was answered 7 times previously.

 

[should]

Hello sir, what is saltwater used for? Sodium chloride solution?

 

[Aisabelcosta]

Hi @G.Patton , I'm thinking of using 41232-97-7 instead of 5449 and I want to follow your guide on "P2P synthesis from glycidate ethers", and I have a questions;
- Do you think I'll get good results with CAS 41232? - For hydrolysis, can I use 85% phosphoric acid instead of sulfuric or HCl?, How much phosphoric acid for 100g of BMK?
- Are layers generated during hydrolysis? At what points?

I would be very grateful if you could help me decide whether to do it or not.

Thanks

 

[G.Patton]

Hello, 41232-97-7 is also BMK glycidate, so that synthesis the same, man.

 

[Aisabelcosta]

Ok, I've read it again and I'm wrong, the only previous step is to dissolve KOH in water and let it cool to room temperature. From here it is equal to 5449, is that correct?

 

[G.Patton]

Dear @Aisabelcosta , I already answered you, that you as about ethyl glycidate ester. There is clearly said in tutorial:
I really don't understand what is a problem do you have now.

 

[should]

Hello sir, can mercury nitrate in the subsequent synthesis of aluminum mercury be replaced by mercury iodide or mercury sulfate?

 

[G.Patton]

No. It can't. Mercury sulphate is very toxic substance and unpleasant for handling.