Separación de isómeros de metanfetamina mediante ácido tartárico

[Mr Good Cat]

@G.Patton general, ¿no es más sencillo utilizar ácido d-tartárico CAS No. 147-71-7 pero en proporciones mucho menos molares en torno a 1 (base):0,2-0,5 (d-tartárico)? Las proporciones exactas podrían estimarse con una simple prueba.

 

[G.Patton]

Sí, se puede utilizar ácido d-tartárico nº CAS 147-71-7, pero es más caro y algunas personas no tienen acceso a él. El ejemplo se muestra con la opción más barata y sencilla.

 

[Bmth]

Cierto que no produce cristales, ¿puede ayudar a que exista el tartarato correcto, o tal vez la fórmula de la sustancia

 

[Bmth]

Bis ¿Puede darme instrucciones sobre el procedimiento o un enlace al mismo? Muchas gracias.

 

[Bmth]

Atau y ¿O es éste? Por favor, ayudar a estos expertos han intentado la 4 ª vez que tengo un fracaso.

 

[G.Patton]

Se dice claramente qué sustancia hay que utilizar. ¿Qué problema tiene?

 

[OrgUnikum]

The main problem with this method is that one gets l-Meth, to be more precise one gets from slightly enriched l-Meth to predominantly l-Meth depending on how long one lets it crystallize out. The more time the more l-Meth is in the cristalline mass. When good stirring is employed the result will be even more l-meth in the crystals (in relation of course).
The good thing s that one gets pretty decent d-Meth fromm the mother liquor.

It does not matter if one uses l-tartaric or d-tartaric or d/l tartaric - it will always be l-Meth what crystallizes out most. It is completely different from Amphetamine btw. cannot be compared at all. I actually understood what is really going on only a short time ago and I fully understand why somebody might believe I am wrong, but well, I am not.

As I try not to criticize when I cannot offer an alternative, here it is:
7.84 g (0.0525 mol) racemic N-methylamphetamine and 9.73 g (0.0525 mol) racemic N-methylamphetamine hydrochloride were dissolved in 70 ml of abs. ethanol and 7.91 g (0.0525 mol) R,R tartaric acid (L-(+)-tartaric acid) in 56 ml of abs. ethanol.
Strong stirring for twenty two hours. room temperature, then the mixture is cooled in the fridge, the formed salt is filtered out and the mother liquor is worked up by A/B extraction and recrystallisation to yield almost exclusively d-Meth.

Its all in the literature. Just not in one place but a bit obfusicated.

Good luck

 

[cruz]

Can we use ethanol contains denatonium for washing or in the crystallization stage? Denatonium in it won't make a problem?

 

[G.Patton]

Of concourse it will.

 

[cruz]

Can I use this tartaric acid? It's L(+)- tartaric acid. Seller said there 2 kinds of L tartaric acid. L (-) AND L(+). L(+) means dl tartaric acid.

A

 

[DREWJACK123]

How would the procedure differ if you had bought racemic cartel dope on the streets and want to separate isomers.i just got d,l tartaric acid I have all the reagents and just got a hot plate/magnetic stirrer. Would you just skip the first steam distillation step and go straight into freebasing and then adding the tartaric and ethanol? I got the ethanol from hand sanitizer and leeched out the glycerin with salt.it was already 70 percent so it should be at least 88 now. And when I'm precipitating the hcl salt does it not snow right away like a regular gas session. Do you just gas it then wait for it to precipitate I don't understand that part.

 

[finch3523]

could you separate dex/levo amphetamine with tartaric acid first and then from the dex amphetamine create dex methamphetamine or would this not be advised?

 

[William D.]

For higher yields, it is better to methylate first.