Lihtne metülooni süntees (bk-MDMA)

[karamelosanto]

HI, Tänan selle sünteesi jagamise eest, ma arvan, et see on väga selge.
Ma olen Lõuna-Ameerikast ja siin on veidi raske leida DCM-i. Kuid ma võin proovida seda kuidagi leida. Võib-olla osta seda Hiinast.
Ma tahan küsida. Kas te saate panna kõik regendid loetelusse koos kogustega, et oleks veidi lihtsam mõista, mida ma pean ostma. Kui on võimalik koos hinnangulise hinnaga.
Tänud!!!

 

[Professor11]

Pode me mandar uma mensagem? Sou da América do Sul também, estou iniciando na produção de Metilona.

 

[Marvin "Popcorn" Sutton]

Tabelis on 40% metüülamiini tihedus 0,89 g/cm3 , seega saadakse 20 ml-s 7,18 g puhast metüülamiinigaasi.
Võrdleme metüülamiini ja selle hüdrokloriidi molekulmassi:
M (CH3NH2)HCl = 67,518 g/mol
M CH3NH2 = 31,057 g/mol.
Suhe = 2,174
Kui kasutate sünteesi proportsioone, siis vajate 15,6 g metüülamiinvesinikkloriidi, et asendada 20 ml 40% metüülamiini lahust.
Metüülamiinvesinikkloriid tuleb eelnevalt lahustada proportsioonis 1g ja 2,5ml vee vahel (15,6g ja 39ml).
Valmistatakse naatriumhüdroksiidi (NaOH) lahus 18g ja 54ml vett, lastakse sellel jahtuda ja valatakse see kolbi koos 2-bromo-3,4-metüleendioksüpropiofenooni lahusega. Seejärel lisatakse metüülamiinvesinikkloriidi lahus. Seejärel jätkatakse vastavalt juhistele.

 

[arundo]

Hello, I'm doing the math, and I see that the molar ratio of NaOH isn't equivalent with methylamine HCl. It doubles. It's for some reason?

 

[antrax]

Ma tahan proovida bk-MDMA keemilist sünteesi Ma juba ostsin kõik vajalikud kemikaalid, ma alustan otse lähteainest 2-Bromo-3',4'-(metüleendioxy)propiophenone (CAS number: 52190-28-0), kuna ma juba ostsin selle Hiina kemikaalide tarnijalt ja maksin 280 dollarit 1kg eest koos saatmisega, alates 25 kg maksan 200 dollarit iga kg eest.
kg koos saatmisega.

Ostsin metüülamiini 40% vesilahust Poola tarnijalt, kuigi selle leidmine ei olnud kerge ülesanne, ja muud keemiatooted on kergesti kättesaadavad riiklikul turul, välja arvatud 36% soolhape, leidsin ainult 35-38% analüütilist soolhapet, mida ostsin, magneesiumsulfaati ma ei teadnud, millist osta, seega ostsin veevaba.

Ácido clorhídrico 35-38% AGR Reag.Ph.Eur.

HCl

www.letslab.com

Magnesio Sulfato anhidro GLR

MgSO4

www.letslab.com

Järgin järgmist bk-MDMA keemilist sünteesi, kuna see tundub lihtsam kui teie poolt jagatud, kuid ma võin eksida, palun teie arvamust.

http://bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/threads/bk-mdma-synthesis-easy-and-fast-method.6423/

Aitäh!!!

 

[Eddybeaumont]

hello mate, can you give me an address to buy cas 52190-28-0 please?

 

[Osmosis Vanderwaal]

Someone asked me the other day about using sesamol to get MD-P1P, and it looked possible. Any opinion on that?

 

[William D.]

Doubtful route. If someone says how to do it simple, we will be glad.

 

[Wan Jack]

In a reaction kettle equipped with a condensing reflux, stirring, dropping and heating device, 111.3 g of catechol, 500 ml of dichloroethane and 166 g of ZnCl2 were added, stirred, cooled to 0-5°C, and 140 g of propionyl chloride was slowly added dropwise for about 2 hours, then the temperature was raised to 20°C and the reaction was continued for 15 hours. After the reaction was completed, water was added for dilution, and the organic phase was separated. The organic phase was sequentially acid-washed and washed with water, dried with sodium sulfate, desolventized, and the residue was recrystallized from ethanol to obtain 144 g of solid 3,4-dihydroxypropiophenone with a melting point of 145-146°C, a content of 98%, and a yield of 85%.

 

[William D.]

Yes, this method is more understandable. But I heard that you can use iodine as a Lewis acid catalyst. For more moderate conditions. I did not have time to check it, but I think that there is need study. Because the chinese intermediate of this substance have is of very poor quality, I think they have problems with the synthesis.

 

[Wan Jack]

Please refer to the next step( Patent: US1964973 , 1932)

 

[Wan Jack]

Sesamol Obtain MD-P1P No relevant information found

 

[Wan Jack]

Preparation of 3,4-methylenedioxypropiophenone
Methanesulfonic acid (MSA, 288 g) and propionic anhydride (156 g) were charged into a 1-liter reaction flask. The mixture was cooled to 0°C and 122 g of 3,4-methylenedioxybenzene (MDB) was added under stirring. The reaction mass was maintained at 0°C to 5°C for 4 hours under stirring. After the completion of the reaction, the reaction mass was diluted with water and the 3,4-methylenedioxypropiophenone product and unreacted MDB were extracted using toluene. The toluene layer was distilled to recover 13 g of unreacted MDB and obtain 142 g of 3',4'-methylenedioxypropiophenone (GC purity > 98%, yield 131% w/w based on consumed MDB). The water layer was distilled to recover 273 g of MSA (purity > 98%), which could be reused in subsequent batches.