Šī reakcija ir ļoti laba nelielā mērogā
Liela apjoma reakcijā, mēģinot kontrolēt eksotermu un lielo putu daudzumu, lēnām ielejot CuCl2 šķīdumu kolbā, netiks iegūts liels iznākums, var palikt tikai nitroalkāni un nanodaļiņu koncentrācija būs pārāk maza, lai samazinātu nitro, jāizmanto pēc iespējas lielāka kolba un viss CuCl2 šķīdums jāpielej uzreiz.
Liela apjoma reakcijā, mēģinot kontrolēt eksotermu un lielo putu daudzumu, lēnām ielejot CuCl2 šķīdumu kolbā, netiks iegūts liels iznākums, var palikt tikai nitroalkāni un nanodaļiņu koncentrācija būs pārāk maza, lai samazinātu nitro, jāizmanto pēc iespējas lielāka kolba un viss CuCl2 šķīdums jāpielej uzreiz.
- By waltjr5858
But when you add all of the cucl2 at once the whole mixture turns black and then within minutes the catalyst falls out of the alcohol and doesn't do much down low... adding drop wise allows a continuous supply of copper to stay in the upper layer acting as a catalyst. So far I have found if you have too much nabh4 left at the time of adding the copper the copper gets reduced wayyy to fast and losses its catalyst activity instead of almost starting as a yellow or brown mixture and slowly turning black before finally falling to the bottom. Thise are the reactions that really work for me when the borohydride amount is low enough to not instantly reduce the copper to black and need the temperature increase to finally cause it to be fully reduced and settle in the bottom slowly over time.... but trying to get the perfect amount of nabh4 at that moment is let's say.... very difficult. Surprisingly the nitro doesn't need much nabh4 in the end to reduce.
