That was the longest meth synth I have ever seen in my life, and extremely old fashion, overkill of silica, overkill of solvent. End product heavily contaminated. You obviously have good lab skills, but that's all in my opinion. I would make this within 10-12 hrs in same yield and definitely much less contaminated and snow white end product (re-crystallize at least twice) in same yield or even a few grams more.
That was the longest meth synth I have ever seen in my life, and extremely old fashion, overkill of silica, overkill of solvent. End product heavily contaminated. You obviously have good lab skills, but that's all in my opinion. I would make this within 10-12 hrs in same yield and definitely much less contaminated and snow white end product (re-crystallize at least twice) in same yield or even a few grams more.
Hello. How do you determine contamination by its appearance, dear chemist? We are looking forward your synthesis report on the Forum. Prove your words please.
Again extracting with DCM amphetamines, overkill of silica and sulfate but this is the only way of doing it with methylamine water solution, i have experience preparing the imine with methanolic methylamine, add nabh4 in portions and stir for 24H, 90% conversation imine to amine.
That was the longest meth synth I have ever seen in my life, and extremely old fashion, overkill of silica, overkill of solvent. End product heavily contaminated. You obviously have good lab skills, but that's all in my opinion. I would make this within 10-12 hrs in same yield and definitely much less contaminated and snow white end product (re-crystallize at least twice) in same yield or even a few grams more.
It's almost a 100% conversion of the P2P and it's pH 1 of course it's gonna be pink if you don't recrystallize lol Report your synthesis in detail if it's that good please.
Hello. How do you determine contamination by its appearance, dear chemist? We are looking forward your synthesis report on the Forum. Prove your words please.
I have done this since 1991 Mr. Patton. "Cooking" we did in EU back in the 1980s-1990s, 2000-2018 it was all Parr Shakers and Büchi reactors (also home build from SS school kitchen food cooking supply) or cheap reactors imported from India. But last 2-3 years most mid to mega labs years works almost exclusively with ultrasound. By cooking molecules crash / mix into each other now & then (that's why it takes time), at pressure things gets going on much faster + higher yield + cleaner. With ultrasound molecules crash into each other 10 000's times per second at an incredible speed nothing else can match and you have your product in a few hrs. I enjoy watching the videos here, they are very well made, but the chemistry here is stone age and nothing for me. I'm retired, I quit this 2 yrs ago.
If you wonder how we lately made dextro-meth (ICE direct, without racemat DL- separation)... import CAS 16251-45-9 from China (can only be bought in minimum 2.5 Kgs drum, price 844 USD/Kg), methylate it (super simple), then hydrogenation that intermediate 4 hrs, super fast simple ulra clean non-hazard non-contaminated reaction at only 2 atm, 90-95% yield.
It's the most fool proof method I have ever came across during my +30 in the underground speed manufacture in Benelux
A method of making a phenylethylamine of formula B: wherein R 2 , R 3 , R 4 , R 5 , R 6 , R α , R β and R n are each independently selected from hydrogen, alkyl, acyl, aryl, amido, amino acids, sugars...
I have done this since 1991 Mr. Patton. "Cooking" we did in EU back in the 1980s-1990s, 2000-2018 it was all Parr Shakers and Büchi reactors (also home build from SS school kitchen food cooking supply) or cheap reactors imported from India. But last 2-3 years most mid to mega labs years works almost exclusively with ultrasound. By cooking molecules crash / mix into each other now & then (that's why it takes time), at pressure things gets going on much faster + higher yield + cleaner. With ultrasound molecules crash into each other 10 000's times per second at an incredible speed nothing else can match and you have your product in a few hrs. I enjoy watching the videos here, they are very well made, but the chemistry here is stone age and nothing for me. I'm retired, I quit this 2 yrs ago.
If you wonder how we lately made dextro-meth (ICE direct, without racemat DL- separation)... import CAS 16251-45-9 from China (can only be bought in minimum 2.5 Kgs drum, price 844 USD/Kg), methylate it (super simple), then hydrogenation that intermediate 4 hrs, super fast simple ulra clean non-hazard non-contaminated reaction at only 2 atm, 90-95% yield.
It's the most fool proof method I have ever came across during my +30 in the underground speed manufacture in Benelux
A method of making a phenylethylamine of formula B: wherein R 2 , R 3 , R 4 , R 5 , R 6 , R α , R β and R n are each independently selected from hydrogen, alkyl, acyl, aryl, amido, amino acids, sugars...
Any serious cooker should invest in an AMAR Equipments reactor, the worlds most cheap high quality reactors, it's really good stuff and quality definitely comparable to EU-made stuff that cost 500% more. You cn have a very goof one 5L AMAR reactor 2500psi with electric stirrer & heating/cooling mantlef or below $10,000
It's interesting, but this modern method will be commercially impractical. Meth from this NaBH4 stone-age method 1kg cost approximately 483 kg per kg (but racemic one) in accordance current market prices for reagents. It's at a first glance evaluation. Nevertheless, thanks for your minds.
Cualquier cocina seria debería invertir en un reactor de AMAR Equipments, los reactores de alta calidad más baratos del mundo, es material realmente bueno y de calidad definitivamente comparable a los fabricados en la UE que cuestan un 500% más. Puede tener un reactor AMAR de 5 litros y 2500 psi muy tonto con agitador eléctrico y manto de calefacción/refrigeración o menos de $ 10,000
Está muy bien todo lo que nos cuentas y no es que dude de tus 30 años de fabricación. Pero la esencia de este foro es compartir los conocimientos que tienes con los demás e incluso puedes aprender algo de algún miembro del foro, aunque lo dudo porque crees que ya lo sabes todo. Si es así, no sé por qué pierdes el tiempo en lugares como este...
Any serious cooker should invest in an AMAR Equipments reactor, the worlds most cheap high quality reactors, it's really good stuff and quality definitely comparable to EU-made stuff that cost 500% more. You cn have a very goof one 5L AMAR reactor 2500psi with electric stirrer & heating/cooling mantlef or below $10,000
Everything you tell us is very good and it's not that I doubt your 30 years of manufacturing. But the essence of this forum is about sharing the knowledge you have with others and you may even learn something from a member of the forum, although I doubt it because you think you already know everything. If so, I don't know why you waste your time on places like this......
It will be dissolved in IPA, but it evaporates quite fast. You have to keep it in a back mind during manipulations and do them quickly. That's why the flask have to be sealed.
Yes i was looking to do some methylamine solution into methanol and now nearly impossible to get solution ready made so ill have to go from:
Methylamine hcl to methylamine into water then
Methylamine into methanol
Ill have to do like this but instead of the ipa ill use methanol ?
Ps: ive tried your way to do by distilation with pre dried the fume and silica gel into methanol to receve the methylamine but ive gone up to 80 and no weight was added.into the methanol and methanol was around more than -30°c
Excellent synthesis, professionally made.
I will add a few ideas from myself:
1. Isopropyl alcohol with aqueous solution of methylamine and then drain the solution with a drainage is not very effective, the drainage can not absorb all the water. It is much easier to saturate the aqueous solution of methylamin with salt and the excretion of methylamine gas is passed over anhydrous alkali, then dissolve gas in cold alcohol.
2. The torn mixing made sure of the techniques, that is, to the suspension of sodium borhydrid in alcohol, a solution of ready -made Imin is buried in alcohol. Justified by a decrease in the probability of hydrolysis.
3. After the recovery stage, it seems to me it is much more convenient to distill, there is no water in the solution, you can not be afraid of steam distillation. The second option to add sulfuric acid to an acidic reaction and also distill alcohol, also the acid will destroy derivatives, and then dissolve the remainder in alkaline water and collect the free base of the amin with dichlormethane.
Hello. How do you determine contamination by its appearance, dear chemist? We are looking forward your synthesis report on the Forum. Prove your words please.
would yall let the man cook. these videos are clean, did you see how he quenched the hcl. yall all talk a good game but this guys putting on a clinic and has enough balls to put a video on the clearnet. salute to you sir
I have been reading this site for a while. Thanks for gathering valid information and putting it on one place.
The video is amazing like always. However, I have some questions. Can someone just use methylamine into an alcohol base instead? E.g. absolute ethanol. Just to avoid the water....
Also can someone just use Sodium cyanoborohydride instead, if so, how to avoid the hydrogen cyanide (HCN)? Any other tips with this chemical as well? Thanks.
I have done this since 1991 Mr. Patton. "Cooking" we did in EU back in the 1980s-1990s, 2000-2018 it was all Parr Shakers and Büchi reactors (also home build from SS school kitchen food cooking supply) or cheap reactors imported from India. But last 2-3 years most mid to mega labs years works almost exclusively with ultrasound. By cooking molecules crash / mix into each other now & then (that's why it takes time), at pressure things gets going on much faster + higher yield + cleaner. With ultrasound molecules crash into each other 10 000's times per second at an incredible speed nothing else can match and you have your product in a few hrs. I enjoy watching the videos here, they are very well made, but the chemistry here is stone age and nothing for me. I'm retired, I quit this 2 yrs ago.
If you wonder how we lately made dextro-meth (ICE direct, without racemat DL- separation)... import CAS 16251-45-9 from China (can only be bought in minimum 2.5 Kgs drum, price 844 USD/Kg), methylate it (super simple), then hydrogenation that intermediate 4 hrs, super fast simple ulra clean non-hazard non-contaminated reaction at only 2 atm, 90-95% yield.
It's the most fool proof method I have ever came across during my +30 in the underground speed manufacture in Benelux
A method of making a phenylethylamine of formula B: wherein R 2 , R 3 , R 4 , R 5 , R 6 , R α , R β and R n are each independently selected from hydrogen, alkyl, acyl, aryl, amido, amino acids, sugars...
That was the longest meth synth I have ever seen in my life, and extremely old fashion, overkill of silica, overkill of solvent. End product heavily contaminated. You obviously have good lab skills, but that's all in my opinion. I would make this within 10-12 hrs in same yield and definitely much less contaminated and snow white end product (re-crystallize at least twice) in same yield or even a few grams more.
Hello. I have read quite a few articles about methamphetamine. too many formulas, it makes me confused. Do you have a simplified way to synthesize P2P into methamphetamine? please guide me
That was the longest meth synth I have ever seen in my life, and extremely old fashion, overkill of silica, overkill of solvent. End product heavily contaminated. You obviously have good lab skills, but that's all in my opinion. I would make this within 10-12 hrs in same yield and definitely much less contaminated and snow white end product (re-crystallize at least twice) in same yield or even a few grams more.
Everything you tell us is very good and it's not that I doubt your 30 years of manufacturing. But the essence of this forum is about sharing the knowledge you have with others and you may even learn something from a member of the forum, although I doubt it because you think you already know everything. If so, I don't know why you waste your time on places like this......
I have not yet succeeded in making methamphetamine. I want to ask the master for advice. Why can't the product with the boiling point of free methamphetamine be directly distilled out after the NaBH4 reduction reaction is completed? I want to know the principle.
I have not yet succeeded in making methamphetamine. I want to ask the master for advice. Why can't the product with the boiling point of free methamphetamine be directly distilled out after the NaBH4 reduction reaction is completed? I want to know the principle.
thank you sincerely! I have followed the instructions in the video and found that pure free amphetamine needs to be added to HCI
I just accidentally mistook chlorine for hydrogen chloride
Later, I heated 32% HCI at 60 degrees and imported it into RM and measured the pH value of 8, which was almost unchanged. Sorry, I have not succeeded in producing amphetamine hydrochloride. The question may be stupid.
Will that be the same ratio or higher amount as its a weaker reducing agent?
Should we worried about any of the hydrogen cyanide (HCN) released ? Planning to just run a carbon filter away from work station and down wind, will this be good enough? Of course, wearing air filtered masks at the same time etc.
Will that be the same ratio or higher amount as its a weaker reducing agent?
Should we worried about any of the hydrogen cyanide (HCN) released ? Planning to just run a carbon filter away from work station and down wind, will this be good enough? Of course, wearing air filtered masks at the same time etc.
If the reduction effect is worse than NaBH4, the dosage should be increased. If you are worried about gas leakage, you can buy a gas storage bag, which is specially used to contain chemical gases. Be sure to seal it tightly to prevent leakage.
Will that be the same ratio or higher amount as its a weaker reducing agent?
Should we worried about any of the hydrogen cyanide (HCN) released ? Planning to just run a carbon filter away from work station and down wind, will this be good enough? Of course, wearing air filtered masks at the same time etc.
I guess the same molar ratio. Pay attention that NaCN forms during the synthesis with NaBH3CN. It's extremely toxic substance, like other soluble cyanide salts, is among the most rapidly acting of all known poisons. NaCN is a potent inhibitor of respiration, acting on mitochondrial cytochrome oxidase and hence blocking electron transport. This results in decreased oxidative metabolism and oxygen utilization. Lactic acidosis then occurs as a consequence of anaerobic metabolism. An oral dosage as small as 200–300 mg can be fatal.
I guess the same molar ratio. Pay attention that NaCN forms during the synthesis with NaBH3CN. It's extremely toxic substance, like other soluble cyanide salts, is among the most rapidly acting of all known poisons. NaCN is a potent inhibitor of respiration, acting on mitochondrial cytochrome oxidase and hence blocking electron transport. This results in decreased oxidative metabolism and oxygen utilization. Lactic acidosis then occurs as a consequence of anaerobic metabolism. An oral dosage as small as 200–300 mg can be fatal.
Its just difficult for myself to get NaBH4 and there isnt much infomation how to neutralise NaBH3CN or to watch out for the NaCN. However, I can get Sodium triacetoxyborohydride (NaBH(OAc)3 - STAB). Any tips using this reducer ? I know its a milder one, therefore I have to increase the mols/weight.
Its just difficult for myself to get NaBH4 and there isnt much infomation how to neutralise NaBH3CN or to watch out for the NaCN. However, I can get Sodium triacetoxyborohydride (NaBH(OAc)3 - STAB). Any tips using this reducer ? I know its a milder one, therefore I have to increase the mols/weight.
