Need help convert bmk 5449-12-7 to free base A-oil
- Thread starter Saul
- Start date
There are some things I don't get in this syntheses
if we just start the syntheses from P2P
how is it possible that this one here is totally different from other
synth posted on this forum ?
if we just start the syntheses from P2P
how is it possible that this one here is totally different from other
synth posted on this forum ?
Can someone with know please explane this last step because there are no answers to find. @HEISENBERG
Hello, it is wrong topic to ask. Look at here 1-Phenyl-2-propanone (P2P) Leuckart amination to amphetamine and methamphetamine.
this picture comes from @serialz pdf file
and this is on topic .
N-formylamphetamine is what we have as a final product started from bmk salts 5449-12-7
and idd the last step is this picture posted today.
I try it also with no luck
www.bbzzzsvqcrqtki6umym6itiixfhni37ybtt7mkbjyxn2pgllzxf2qgyd.onion/attachments/t6r0hfllrj-jpg.7360/
left N-formy right P2P
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This method, which I linked in message above, is described last step of hydrolysis from N-formylamphetamine
would be nice if someone can translate this to normal words
what means
***** CONCENTRATED HCL 10M HCL 10ml
***** THIS SOLUTION WAS BASIFIED WITH SODIUM CARBONATE AND EXTRACTED IN TOLUEEN 3X50ml
***** THEN DRIED OVER ANHYDROUS SODIUM SULFAAT
***** HCL GAS WAS GENERATED NACI ( KITCHEN SALTS ) AND CONCENTRATED SULFONIC ACID WAS BUBBELING TRUE THE SOLUTION
UNTIL A PRECIPITATE WAS OBSERVED
AND SO ON AND ON
this post contains so many unanswered questions.
all the experts do is answer with an existing link where you don't find the answer to the question at all.
they usually link you to a completely different preparation method.
I have the impression that braking bad is all about buying as many different chemical products as possible.
It is time to answer the questions that are being asked. without replying with an existing link .
this preparation here can be made quite cheaply and with legal products. I really don't understand why this isn't getting more attention.
it would be better if the forum invested in professional people
I think a lot of users are willing to pay for this.
so it's a win win situation
all the experts do is answer with an existing link where you don't find the answer to the question at all.
they usually link you to a completely different preparation method.
I have the impression that braking bad is all about buying as many different chemical products as possible.
It is time to answer the questions that are being asked. without replying with an existing link .
this preparation here can be made quite cheaply and with legal products. I really don't understand why this isn't getting more attention.
it would be better if the forum invested in professional people
I think a lot of users are willing to pay for this.
so it's a win win situation
How do you make a 10 M HCl solution?
Answer 1
Add 8.26 mL of concentrated HCl to about 50 mL of distilled water, stir, then add water up to 100 mL. Mass percent solutions are defined based on the grams of solute per 100 grams of solution.
Answer 2
10M HCl indicates that the solution has a concentration of 10 moles per liter. To do this, it is necessary to add a ratio of 365 grams of HCl per liter of water.
People, please take some time to search with me for answers off this
picture. this is the only right way to do the last step.
if this picture is explane in normal lang we all can make freebase at the cheapest way possible.
leth this topic be legandary with your help .
Answer 1
Add 8.26 mL of concentrated HCl to about 50 mL of distilled water, stir, then add water up to 100 mL. Mass percent solutions are defined based on the grams of solute per 100 grams of solution.
Answer 2
10M HCl indicates that the solution has a concentration of 10 moles per liter. To do this, it is necessary to add a ratio of 365 grams of HCl per liter of water.
People, please take some time to search with me for answers off this
picture. this is the only right way to do the last step.
if this picture is explane in normal lang we all can make freebase at the cheapest way possible.
leth this topic be legandary with your help .
I'm so sorry that you can't find information in our forum. I link to other post because we already wrote manuals with answers to your questions. It was done in order to help maximum amount of people. I can't write same in every theme.
Which question is unanswered? I made detached topic with clear reaction explanation P2P synthesis from BMK glycidate ethers. You are still unsatisfied.
You absolutely right. It is always better to pay for work to professionals instead of learn something absolutely new for you. Some people here try to figure out information and we try to help them. You have to understand that we can't give you basic chemistry knowledge. We not a school chemistry class, we just help with correct direction in own learning to beginners.
Which question is unanswered? I made detached topic with clear reaction explanation P2P synthesis from BMK glycidate ethers. You are still unsatisfied.
You absolutely right. It is always better to pay for work to professionals instead of learn something absolutely new for you. Some people here try to figure out information and we try to help them. You have to understand that we can't give you basic chemistry knowledge. We not a school chemistry class, we just help with correct direction in own learning to beginners.
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7.2.4 Synthesis of Amphetamine hydrochloride
N-Formylamphetamine (1.31g, 8.03 mmol) and concentrated 10M HCl (10mL) were
combined and heated to 130° C for 2 hr.
The reaction was cooled, poured into water (200mL).
This solution was basified with sodium carbonate and extracted into toluene (3 x 50mL),
then dried over anhydrous sodium sulfate.
HCl gas was generated
(NaCl and concentrated sulfuric acid) was bubbled through the solution until a precipitate was
observed,
the solvent was evaporated to afford 2-amino-1-phenylpropane hydrochloride
as a brown solid (0.6 g)
which was recrystallised from acetone to give a white solid
m.p. 145-147° C
(lit? 146-147° C). HPLC analysis indicated the purity of the
hydrochloride salt to be 82%,
the yield of this reaction was (0.49 g, 37%).
'H NMR (200 MHz) 8: 1.4 (d, 3H, CHs), 3.05 (m, 2H, CH2), 3.55 (m, 1H, CH),
7.3 (m, 5H, ArH).
Gas chromatograph retention time: 4.30 minutes.
Mass Spectrum (EI) m/z: 135 (0.005%, M”"), 44 (100%), 91 (36%), 65 (27%), 42
(18%), 51 (11%).
Infrared spectrum Vmax / cm’! Aromatic C-H 3000, N-H 3450.
