Sinteza 4'-metilpropiofenona iz toluena s Friedel-Craftsovo reakcijo (merilo 1 kg+)
- Thread starter WillD
- Start date
Da, na primer železov klorid (FeCl3) in cinkov klorid (ZnCl3), vendar bo reakcija potekala počasneje v primerjavi z uporabo aluminijevega klorida.
- By CryoThio
Cink in železov klorid sta brezvodna?
Pri katerem od teh dveh pride do hitrejše reakcije?
Pri katerem od teh dveh pride do hitrejše reakcije?
Da, oba sta brezvodna in od obeh bi se najbolje obnesel železov (iii) klorid (FeCl3)
pri tej sintezi imam samo grelnik balonski mešalnik ali ne morem uporabiti vodne kopeli in koliko stopinj ne smemo preseči, ko dodajamo propinol klorid
V tej sintezi je AlCl3.6H2O, ali ga lahko uporabim kot katalizator?
- By CryoThio
Prepričan sem, da mora biti to brezvodni aluminijev klorid.
Brez vode. Problem je, da aluminijevega klorida ne moreš posušiti s segrevanjem, če se ne motim.
Vendar to še enkrat preveri.
Brez vode. Problem je, da aluminijevega klorida ne moreš posušiti s segrevanjem, če se ne motim.
Vendar to še enkrat preveri.
V tej sintezi bom uporabil cinkov klorid Koliko g cinkovega klorida naj uporabim v tej sintezi?
**Propionyl Chloride (CH₃CH₂COCl):**
* Molar mass: 109.5 g/mol
* Number of moles: 1000 g / 109.5 g/mol ≈ 9.13 mol
Toluene (C₇H₈):** **2.
* Molar mass: 92 g/mol
* Density (25°C): ≈ 0.87 g/mL
* Mass: 3000 mL * 0.87 g/mL = 2610 g
* Number of moles: 2610 g / 92 g/mol ≈ 28.4 mol
**Aluminum Chloride (AlCl₃):**3.
* Molar mass: 133.5 g/mol
* Number of moles: 1500 g / 133.5 g/mol ≈ 11.2 mol
**Mole Ratios:**
Now, let's determine the mole ratios by proportioning the mole numbers to each other. Let's ratio according to the smallest number of moles (here propionyl chloride):
** **Propionyl Chloride : Toluene : AlCl₃**
* **9.13 mol : 28.4 mol : 11.2 mol**
* **Molar ratios - 1 : 3.11 : 1.23**
This implies a ratio of approximately 1:3:1.
* Molar mass: 109.5 g/mol
* Number of moles: 1000 g / 109.5 g/mol ≈ 9.13 mol
Toluene (C₇H₈):** **2.
* Molar mass: 92 g/mol
* Density (25°C): ≈ 0.87 g/mL
* Mass: 3000 mL * 0.87 g/mL = 2610 g
* Number of moles: 2610 g / 92 g/mol ≈ 28.4 mol
**Aluminum Chloride (AlCl₃):**3.
* Molar mass: 133.5 g/mol
* Number of moles: 1500 g / 133.5 g/mol ≈ 11.2 mol
**Mole Ratios:**
Now, let's determine the mole ratios by proportioning the mole numbers to each other. Let's ratio according to the smallest number of moles (here propionyl chloride):
** **Propionyl Chloride : Toluene : AlCl₃**
* **9.13 mol : 28.4 mol : 11.2 mol**
* **Molar ratios - 1 : 3.11 : 1.23**
This implies a ratio of approximately 1:3:1.
It doesn't matter anymore, I've given up on this project.
Boiling points of toluene and 4'-methylpropiophenone under vacuum damper pressure.
20 mmHg.
Toluene 16.55 degrees.
4'-methylpropiophenone 123-126 degrees
20 mmHg.
Toluene 16.55 degrees.
4'-methylpropiophenone 123-126 degrees
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MDA Synthesis. Part 1 of 3.