Mephedrone Purification

Mephedrone Purification

Introduction
Mephedrone (4-MMC) synthesis reaction is carried out with production of some amount of by-products. Also, some amount of unreacted precursor is left in the reaction mixture after reaction. It takes to purify 4-MMC product with insufficient purity to reduce health risks. 4-Methyl-N-methylcathinone is a powerful synthetic stimulant drug and cheap euphoretic. Importantly, it is most demanded and wide common. It is known that big number of drugs on dark market are sold without purification (with enormous number of side synthesis substances). Using of these drugs can cause physical and psychological harm. Purification is a way to minimize the risks of drug use.

In this article, a Home Purification Method is shown for dirty mephedrone. You don't need a chemical laboratory, you need a kitchen and some stuff, which you can buy in any pharmacy or public store.

Home mephedrone (4-MMC) recrystallization
You need:

1. A mephedrone for purification.
2. The mixture of ethyl acetate:acetone, 4:1. It takes 20 ml of mixture for 1 g drug.
3. Metal cups for water bath and evaporation procedure.
4. A filter paper or filters for a coffee machine.

Procedure:
Suspension preparation

1. Pour the mephedrone powder into the mixture of ethyl acetate and acetone.
2. Mix it thoroughly until a suspension is obtained.

Heating and evaporation.

3. Put the water bath onto the сooker

Pour the mixture into a metal plate

and place it into the water bath.

Cooling and settling

4. Pure mephedrone will be crystallized partially because it is not solved in acetone, but at the same time it is solved in ethyl acetate partially. Organic side substances, which have to be removed from mephedrone, are solved in acetone.

The solution have to be evaporated by 1/3.

5. After that, wait until the solution would be cooled to room temperature. Put the plate with solution into a fridge for 2 hours (3-5 degrees).
Filtration and washing.

6. Take the plate from your fridge.

7. Scrape off the crystals that have fallen from the side pieces

8. and start filtering

Wash your crystals by an acetone 2-3 times and dry it in an open air.

As you can see, the procedure isn't complicated. It should be noted that the mother liquor (the filtered solution) contain approximately 5-10% of mephedrone. You can evaporate this solution by 3/4, until crystals appearing, and repeat stages №5-8 of the procedure.

Mephedrone Before and After Home Mephedrone (4-MMC) Washing

Home Mephedrone (4-MMC) Washing
One of the most frequent questions is how to clean the purchased drug (crystals/powders). It is also one of the basic skills of an advanced consumer, sometimes the results of such a simple cleaning are striking.

    Why clean if always used as is?

- For example, this is necessary for intravenous use (the cleaner the drug, the safer), in addition, it affects the purity of the exposure, as well as the severity and variety of side effects.

Then, I give a universal instruction, following which you can easily wash not everything from the residues of synthesis by-products, but a lot. If the drug is purified by this method, as a rule, the weight loss of the final product is small.

    How to determine what can be cleaned according to this instruction?

-The main parameter of a suitable drug for cleaning is insolubility in anhydrous acetone and cold isopropyl alcohol. Most of the impurities in street drugs are from laboratories due to negligence in synthesis. And impurities, of course, reduce the shelf life of the drug, spoil the commercial species, worsen the force of exposure, and also increase the risk of poisoning.

Consider a method of purifying mephedrone in powder form

If it's a crystal, it doesn't mean it's clean. Therefore, the mephedrone crystals are cleaned in the same way, ground as much as possible to a uniform state.

The principle of the process is elementary. A filter is assembled from the available means, which will retain mephedrone, but pass flushes with impurities (impurities dissolve in cooled acetone/alcohol, and mephedrone is insoluble). The impurity extractant is then forced out of the filter under pressure, leaving the pure product. If necessary, the process can be repeated by adding a new portion of extractant.

What will be needed and what to do?

  1.   Chilled extractant (anhydrous acetone or absolute isopropanol);
  2.   Mephedrone of any hue and humidity 3 g;
  3.   Cotton wool 0.5x0.5 cm;
  4.   Syringe 5-20 ml 1pc;
  5.   Waste glass;
  6.   Petri Dish (any plate is suitable);
  7.   Pipette 3 ml.

In a syringe, we put a tiny piece of cotton wetted in extractant. It'll hold the clean mephedrone inside. If there is a lot of cotton wool, the design will lose functionality. If the cotton wool is too small, or it does not cover the hole, then part of the mephedrone will come out with the waste.

Creating a filter

We grind mephedrone into dust and pour it into a syringe over the cotton wool, you can slightly compress. A third of the free space for the extractant should remain in the syringe.

Charge the system

Using a pipette, we fill the remains with the syringe with a cooled extractant (in the photo, the extractant is marked with the number 1). As it moves, it will be visible how impurities leave (in the photo you can see in the field at number 2).

Add an extractant

Next, we insert the piston into the syringe cylinder and squeeze the extractant through the mephedrone with some force. The eyes will see how the dirt moves to the filter, and then leaves the syringe in a waste glass.

Extract impurities into a waste beaker

The indicator of mephedrone purity is the color of the extractant drop leaving the filter. The drop should be transparent and without color. If necessary, add fresh extractant to remove impurities without residue.

Complete the washing of mephedrone

The impurity extractant should be discarded. It won't be useful anywhere else.

Extract

The syringe contents are now placed on a Petri dish to further evaporate the extractant residues. We remove a piece of cotton from the mephedrone, it will no longer be useful. The evaporation of the extractant can be accelerated in a water bath or other heating elements.

Lay out the purified mephedrone until it is dried completely

Purified Mephedrone Hydrochloride

Upon reaching a constant weight and the absence of the smell of the extractant, cleaning can be considered completed. This method does not give 99.9% purity of the product, but this is the best of the most affordable and simple. After such cleaning, the substance is suitable for consumption. For greater purity and commercial appearance, the obtained powder can be subjected to a slow recrystallization method (and another recrystallization method).

  1. marsella

    Synthèse de méphédrone (4-MMC) par dissolvant NMP (en grande quantité)

    Mephedrone 
    Schéma de réaction Réactifs 2-Bromo-4'-méthylpropiophenone (cas 1451-82-7) - 5 kg; N-méthyl-2-pyrrolidone (NMP; cas 872-50-4) ou DMSO, DMF, Sulfolane - 20 L; Méthylamine 40% en solution aqueuse (cas 74-89-5) - 8 L; Benzène - 20 L; Acétone - 30 L; Acide...
  2. Brinda

    4-MMC Complete Synthesis

    4-MMC Synthesis Big thanks to @WilliamDampier for providing me with the necessary reagents to synthesize this compound. Abstract 4-MMC is a synthetic stimulant of the amphetamine and cathinone classes. It is chemically similar to the cathinone compounds found in the khat plant of east africa...
  3. SonicNL

    Mephedrone (4-MMC) acidification how do you do it?

    Hi. I was wondering what route you follow in the acidification stage after washing the freeebase. After studying and experimenting, the way I use right now is adding acetone 1:1 volume to the base with HCl solution 1:5 to acetone. This way it is the easiest to control the temperature. I too...
  4. EHRMANTRAUT

    My first synthesis of mephedrone on DCM. + photos.

    I am glad to welcome you. So, my report on the synthesis of mephedrone. write without mood because at the end of the synthesis was made a mistake. about this you will learn at the end of the article. and so everything in order. I got a tester for 4mmms. It contained methylamine, bk4, acetone...
  5. A

    Does the color of the bath salts in their crystal form (bk-MDMA, 4-MMC,MDPV...) define its purity?

    Question 
    For example, if it has a brown, orange color... (that is, dark colors) does it mean that it is impure and if the crystals are transparent, does it mean that they are pure or does the color not define the purity of a drug?
  6. cubesquare

    4-MMC and what you actually get.

    I was having a convo with @Gordon Ramsay and @Heineken about 4-MMC and the topic of testing and quality came up so I wanted to start this thread to capture some of what I have found. Looking at the massive variation in quality, look and feel, texture and dryness found across many vendors...
  7. SonicNL

    4-MMC (mephedrone) in ethylacetate

    Hello, I'm read that synthesis in ethylacetate is pretty fast and results in a pure product, but I can't seem to find enough information on here or somewhere else. AFAIK synthesis in ethylacetate does not need heating and the reaction is completed in 30 - 40 minutes. Who has knowledge about...
  8. SonicNL

    Purifying 2-bromo-4-methylpropiophenone

    Hi I found a suplier which sells me really good 2bk4. But, I want to make sure I wash all impurities out before proceeding to 4-MMC synthesis. How do I do this? The main thing i'm concerned about is 4mpf and bromine. Maybe it isnt neccessary, but I want to purify it anyway Have a good day!
  9. K-Cyanide

    Mephedrone (4-MMC) synthesis; easy to perform- high yielding

    Introduction: In the following, forum members will be presented with a synthesis that is very easy to perform, does not take much time, and gives an exceptionally high yield. The method is a result of many years of experience and inputs from various sources that go back to the times of the...
  10. SonicNL

    4-MMC (mephedrone) synthesis in DCM

    I've tried this synthesis and gotten yields ranging from 30% 45%. Sharing in case it might be helful to others. Vice versa, other people might know changes to this synthesis for higher yields. Improvements are always welcome Needed: 100 g 2-bromo-4-methylpropiophenone 500 ml DCM 200 ml...
  11. SonicNL

    4-MMC (mephedrone) freebase storage

    Hello, after making 4-mmc freebase solution, how long can it be stored? before needing to ad acetone for the precipitate to fall out? To be more precise, how long is the shelf-life of acidified 4-mmc freebase? And how should the product be stored?
  12. S

    Do you think it was Mephedrone?

    Hello everyone, I’m living in iran About 2 years ago some dealer gave me some brown powder and I think I have some G of cocaine ( today in iran call it OD) , with smell of dior perfume and it’s feels like best experience I have ever had (also every one who snorted it fall in love with it) Just...
  13. J

    4-MMC Mephedrone, Tryptamine, and Disso Manufacturer

    Looking for a vendor 
    I'm looking for a 4-MMC or Mephedrone manufacturer. I am also looking for those that can produce or supply 5-meo-mipt HCL, 5-mapb HCL, DCK, and 5-meo-pce (or pcp). I will ignore resellers that gouge prices and those that are inexperienced. I buy in bulk, but I start in smaller amounts that...
  14. GaDjo

    where to buy laboratory glassware and equipment ?

    Question 
    Good morning all I would like to estimate the cost of a lab of 4-MMC and/or amphetamine. For that, I have to look for laboratory glassware. I've tried looking in existing threads, but can't find any advice on where to buy it. So, do you have a site to advise me to buy my first pieces? I'm in...
  15. Mephedrone hydrobromide synthesis

    Mephedrone hydrobromide synthesis

    Mephedrone hydrobromide synthesis from 2-bromo-4'-methylpropiophenone with n-methylpyrrolidone https://bbgate.com/threads/synthesis-of-mephedrone-in-nmp-large-scale.231/
  16. 2-Bromo-4'-methylpropiophenone synthesis from 4'-methylpropiophenone

    2-Bromo-4'-methylpropiophenone synthesis from 4'-methylpropiophenone

    2-Bromo-4'-methylpropiophenone synthesis (CAS 1451-82-7) from 4'-methylpropiophenone with HBr/H2O2 https://bbgate.com/threads/bromination-of-4-methylpropiophenone-with-hbr-h2o2-large-scale.215/
  17. Mephedrone synthesis

    Mephedrone synthesis

    Mephedrone synthesis from 2-iodo-4'-methylpropiophenone (CAS 236117-38-7) with ethyl acetate https://bbgate.com/threads/synthesis-of-mephedrone-in-nmp-large-scale.231/
  18. 2-Iodo-4'-methylpropiophenone synthesis from 4'-methylpropiophenone

    2-Iodo-4'-methylpropiophenone synthesis from 4'-methylpropiophenone

    4'-methylpropiophenone iodination with iodine/cooper (II) oxide https://bbgate.com/threads/iodination-of-4-methylpropiophenone-with-iodine-cooper-ii-oxide-large-scale.218/
  19. 4-MMC (mephedrone) synthesis. Complete video tutorial.

    4-MMC (mephedrone) synthesis. Complete video tutorial.

    https://bbgate.com/threads/4-mmc-mephedrone-synthesis-complete-video-tutorial.616/
  20. Marvin "Popcorn" Sutton

    4-MMC (mephedrone) synthesis. Complete video tutorial.

    This video represent a simple synthesis way of 4-MMC (mephedrone) in a small scale from 4'-methylpropiophenone. There is total synthesis video manual which explain everything and gives opportunity to make 4-MMC to every beginner of organic synthesis. Equipment and glassware: Round bottom...
  • Free product samples

    Testing products from new vendors and manufacturers.

    Get free samples for testing now!

  • Always stay in touch with BB forum. Element/Matrix.

    Connect notifications to always stay in touch with the forum!

    Connect

  • The BB Forum team is looking for cooperation:

    • Traffic arbitrage specialists
    • Spammers
    • Advertising agencies
    • Bloggers/Vloggers
    • TOR sites directories
    • Creative people who can create viral content
    • Administrators of Telegram Channels and Groups

      We will pay more for your traffic than our competitors! $0.1 per visitor!!!If you are interested in, write to the administrator.
Top