GBL synthesis

[rothschild33]

The following is a novel synthesis method for GBL.

excerpt:

source:

An Improved Process For The Production Of Gamma Butyrolactone - Patent

The present invention relates to an improved process for the synthesis of highpurity gamma-butyrolactone by the liquid phase oxidation of tetrahydrofuranwith hydrogen peroxide as environmentally benign oxidant in the presence ofcatalytic amount of selenium (IV) oxide in the temperature range ambient

www.quickcompany.in

I have a question about this procedure. Is it possible to use a lower concentration of hydrogen peroxide such as 30% instead of 50% due to regulatory reasons while adjusting the amount of H2O2 used in the reaction?

 

[Fenster]

The yields are way low, don't waist your THF this way. Just do the GABA > NaNO2 route.

 

[rothschild33]

How is an 88% conversion of THF considered low?

 

[Fenster]

It never works out that way, besides THF is worth more then the final product. Seriously just buy kg of GABA for next to nothing.

 

[kızılkos]

can you explain the gaba method

 

[Billnye195]

Hey guys. I'm new to the community. Does anyone have the synthesis from BDO - GBL? If so please share. This forum is the best thing I've ever seen. Your all legends.

 

[HIGGS BOSSON]

Dehydrogenation of 1,4-Butanediol (BDO) to gamma-Butyrolactone (GBL).​

A mixture of 90.1 g (1 mole) 1,4-butanediol, 4 g of copper chromite catalyst and 0.15 g of powdered reagent grade sodium hydroxide (or better KOH) was stirred vigorously and heated under reflux. At about 200 °C, a lively evolution of hydrogen occurred, and the temperature dropped about 10 °C and the dehydrogenation proceeded smoothly. The evolution of gas (39 L/2 mol per mole 1,4-butanediol reacted) ceased in about 3 h. The reaction mixture was cooled to room temperature, filtered from the catalyst and distilled under reduced pressure to give gamma-butyrolactone in about 80% yield and unreacted 1,4-butanediol in about 10% yield.

GHB (Gamma-Hydroxybutyrate) Synthesis FAQ

 

[T0lek511]

Is better and safer just buy GBL from china as cleaner

 

[BamBam]

Have you got a link to find this cleaner in china. I’ve searched everywhere for something like this and found nothing.

 

[T0lek511]

And cheaper

 

[lucine]

Does none of the pdfs in the link load or download for anyone else?
Can someone post the url to the main pdf document which describes the synth?

 

[evian]

check my listing guy, i sell as a cleaner company