Methamphetamine synthesis from P2P by NaBH4 reduction. Medium-Scale.

[btcboss2022]

Hello,

After many tests using Methylamine HCL based on this method I will share the best way that I found to obtain Methamphetamine freebase in big scale:

• 966 gr P2P​
• 14 liters Methanol
• 1183 gr Methylamine HCL​
• 638gr NaOH​
• 452 gr Anhydrous Sodium Sulfate​
• 105 gr NaBH4​
• 35 L distilled water​
• 7 Liters DCM​

- Fill the reactor with the 14 L of Methanol
- With stirring dissolve the Methylamine HCL
- Put the reactor temp at 0C(not the mixture temp) and add the NaOH, the temp will increase
- Once the temp come back to 20C add the P2P, the temp will increase stir it during 45min-1 hour
- Add 252gr of anhydrous sodium sulfate
- When the mixture temp arrives to 8C start adding portionwise the NaBH4 not exceeding the 20C
- Once all the NaBH4 has been added let it mixing under 20C during aprox 2 hours until the mixture stops bubbling
- Add the water and continue mixing during 5 min
- Add the DCM and mix it during 10 min
- Stop stirring and let layers get separated
- Keep the bottom layer and discard the upper one( not profitable to extract this aqueous phase)
- Add 200gr of anhydrous sodium sulfate to the saved layer and mix it
- Filter it in Buchner Funnel
- Evaporate the DCM
- Clean and smelly Methamphetamine freebase obtained

;-)

 

[ossi]

i have actually Methylamin-Water solution. How to remove water? Water is dangerous in this reaction i think

 

[Hank Schrader]

Chemically speaking, methamphetamine is methamphetamine. No matter what method it is obtained, borohydride or hydrogenation, etc...
But to be honest, NaBH4 methamphetamine is very inferior in terms of time of action and quality.
Perhaps minimal impurities that remain in other production methods and give a specific effect to the product.
In the case of borohydride, the action time is up to 16-18 hours and large dosages of the racemic product.
I think the people who synthesized borohydride methamphetamine would agree with me.
For example, methamphetamine obtained by the leukart method and divided into isomers is effective for almost 2 days.
Received methamphetamine through Sodium borohydride and separated into isomers acts only 16 hours and higher dosage.
The absence of impurities in the base is guaranteed by fractional distillation and division into isomers.
Of course, this sounds very strange, because from a chemical point of view, methamphetamine is methamphetamine, but as practice shows, this is not so.
Using the example of Viagra, I can tell you that fizer is unique in the production of sildenefil, and if you compare it with generics that have a similar amount of active ingredient, you will feel the difference.

 

[Macondor]

and in the MDMA case? can i dm to you?

 

[masiuka]

Dear Colleagues.
I've read that some of you purify meth freebase by steam distillation.
I do not have enough efficient vacuum pump to keep water boiling poing below 60 deg.C so I thought I can instead wash it several times with distilled water.
To my surprise...first try of washing created emulsion that didn't want to break.
Eventually I added enough NaCl to create saturated solution and force the separation and I was able to recover freebase...
...anyway...
Can someone explain my how steam distillation can allow to get separated freebase and water layers and mixing it with water just gives my unbreakable emulsion?
I just don't get it. What's a difference??

 

[w2x3f5]

Use the solvent for extraction, dichloromethane, as an example.

 

[masiuka]

I see I did bad assumption thinking that steam distilled freebase will separate from water itself :-/
I combined the brine I had left with NaOH from reaction slury extract and I extracted it with IPA getting a little more of freebase.
The puny amount, I think, but, as Albert Hoffman said (starting his work in Sandoz), we need to learn working with small amount of chemicals ;-)

Thank you for quick advice

 

[w2x3f5]

alcohol draws water, better use dcm and use MgSO4 or Na2SO4 for dry solvent before distill

 

[Lordoftheshard 2]

I need help I did the reaction one a nice bath from the start the temp did not go above.5celcius only when one addition of nabr it took the temp to 40cekcius for 40secinds to then it went down to 3degrees further addition it never raised the temperature again as I made sure I didn't add as much as the the first addition when U dud do that first addition it had a real cats puss smell to I it after that the other addition no smell I followed everything ti the book I made something cause I had a layer in the DCM but when I went to proceed it with tartaric the l meth was stock to the tartrate buy the liquid which was suppose to have the g meth had nothing
Also with the P2P I did 20,brine washes to raise the oh which di nothing m to pH saturd at 2.5

 

[UWe9o12jkied91d]

depending on scale a nice bath might not be required from the very start, have it ready and use it as needed (if), but as long as your foaming is inside the flask let the reaction proceed without additional cooling
as far as your acidic p2p you could try bicarbonate sol. wash or steam distill your ketone

 

[Lordoftheshard 2]

I did both nothing changed the pH of the ketone I did external steam distillation if the way I do my meth now I found out the that you have to ad water to the flasks the fistill over how much water di I add to the flasks with within 100g of p2p

 

[rothschild33]

I reckon this is a 2 step reaction, imine formation then amine formation. Is there a good indication for imine formation, just to know that the reaction is working for troubleshooting purposes? And is there one for amine as well?

 

[UWe9o12jkied91d]

TLC

 

[Lordoftheshard 2]

I did the internal steam distillation product changed from the orange brown colour to a nice yellow colour and pH has raised to pH 5 can I use this ad is or do I need to raise the pH to 7 as I want to do the reaction again to make product

 

[Lordoftheshard 2]

Did the reaction all went well I worked out I got my ratios for the sodium borohydride wrong in the first attempt and fried the fuck out of things
This time cats piss FB also you don't have to use as much water as stated massive over kill I cut the water down buy a quarter and still . The product came out fine just doing a EU resolution now see how that works out btc thanks for your knowledge and sharing using pseudo to make meth or ppa to make 4 methylaminorex in my past this bmk p2p is a whole new world to me and your information that works I'm highly grateful for
All members if you need a source to acquire all the bmk Methylamine and sodium borohydride from 1kg to 1 ton 100% you will receive your product doesn't matter were you are in the world contact me

 

[Lordoftheshard 2]

Im.gking to be quiet honest and Frank here have any if you tried the product this makes strength wise iits fucken shit yrs you make a product but it does nothing not only me 4 other people said the same thing after producing product for the last 20 years I'm going to tell you all straight unless your reaction has a metal in it don't bother it's the metals that what give the product it's strength leg lithium bitch iodine hypophos/rp p2p aluminium amalgam your reaction has to be one of these else your just waisting time effort and money on producing shit
I'm not having a go at any one I'm just stating the facts thanks to btc bioss keep up the good work I'm going to try and find another method of yours that has metal in so I don't throw this p2p down the toilet all these methods without metal in them are to ifucken.us3l3ss

 

[Macondor]

THIS IS THE SAME FOR mdma USING NaBH4? less potent? why the fuck?

 

[btcboss2022]

Is impossible to discuss something when the main thing are "facts" based on personal feelings without any chemical or scientific argument.
Is very easy to understand pure MDMA is pure MDMA and pure D-Meth is pure D-meth if you obtain the pure product it's a unique compound with a unique molecule structure.

D-Meth

MDMA

If you have these pure and isolated molecules no matter the route you used with metal, without metal even with magical techniques...won't be any difference should be exactly the same.
About strength only could change about impurities(pure product concentration not enough isolated) or enantiomers separation(in that case won't be the exact molecule of the pic)
I can put in your hands 10 samples of pure product obtained with different routes and you never will know the route used on each, won't be distinguishable.

Easy example pure technical distilled H2O is pure H2O you won't know the technique used to get it you just have H2O.

With this I don't want to change your mind or your feelings when you use the product, I'm just explaining contrasted and real facts that could be shown to anybody anywhere with the same results.

Thanks.

 

[Lordoftheshard 2]

Thank you but as Hank said product made this way is weaker your always redosing
I
I've always made product from pseudo or ephedrine and it's always quality Im not putting anyone down and respect what you do for all of us with your synth and information
We did this synth 4tines to make sure there was no error and each time came up with the same result it makes a much weaker product not only me.5 people tested the product and said the same thing
Yes it makes a product no doubt about it as for strength and quality it wasn't there

 

[Lordoftheshard 2]

If I sold that product in my country some one would shoot me its only good for cutters instead of using n -iso we already did tests.with meth made from pseudo and this product mixed and rexaled it's ,$700 cheaper a kilo than buying n-iso
I don't cut my product but I gave me.friend some of this product he mixed it with his pseudo product and recrystallized it

 

[w2x3f5]

I did meth on sodium borohydride, no problems arose when separating with d-tartaric acid in ethyl alcohol. The D-isomer crystallized, the L-isomer remained in the form of a thick oil after distillation of the alcohol. Unfortunately, I did not measure the angle of rotation.

 

[situ1984]

Could you please tell me the steps of hydroiodic acid in ephedrine?

 

[Macondor]

To the MDMA synth happen something similar?
Start from PMK glycidate and reduce with NaBH4 can make lees potent MDMA?
Start from piperonal and reduce with amalgam wil be better or start from PMK glycidate and reduce with amalgam?
please i want to make the best product for myself..i tired of buy shit for consume. yeasr ago..there was a really nice MD stuff...now is shitty shitty

 

[btcboss2022]

Strangely with MDMA is totally the opposite, of all synth I did of MDMA the NaBH4 reduction give more potent product.
I can't explain why because I don't know exactly but I'm practically sure that all is about enantiomers resolution, in that case MDMA is totally racemic no resolution applied. Seems(not sure only based in experience) that NaBH4 is good to obtain good racemic products but not good route if later needs to make a resolution like meth for example.

 

[Woodshack]

Thank-you for your knowledge BTCBOSS! <3

 

[btcboss2022]

You can do exactly the same process replacing NaBH4 by an aluminum amalgam as reductor but the rest the same.

 

[mithyl2]

what can be used instead of DCM?

 

[UWe9o12jkied91d]

xylene, toluene, whitespirt, pether, diethyl ether, freon, propane, benzene, petrol from the pump, zippo lighter fluid get creative ni-

 

[mithyl2]

is there a particular reason why DCM was given as the solvent to use? will i get a lesser yield if i use an alternative?

 

[UWe9o12jkied91d]

No, most likely not, DCM evaporates hella fast, it is why its preffered as an extraction solvent by some chemists.