N-(2-Phenylpropyl)-Piperidinone

[KornerStore]

I was reading the post about fentanyl synthesis, and was hoping someone can give a bit of info or a guide on how to make this precursor to alpha methyl fentanyl. This compound seems like a good candidate for home use, as it's just potent enough to be cheap, but long lasting enough (supposed to be longer lasting than regular fentanyl, can't find by how much) to be more practical.

I know the phenyl 2 bromopropane can be made from allylbenzene and hydrobromic acid, I think, but are there other routes?

 

[G.Patton]

What do you mean "for home use"? This substance extremely potent and can lead to death in case of silly mistake. BB forum team don't recommend you to make it or use in safety reasons.

 

[KornerStore]

Yes, very potent, but imo with the right precautions, like a gas mask, some long clothing to prevent any absorbing through the skin, wiping everything down after and during synthesis to get any left overs, perhaps even some naltrexone/naloxone before hand to be extra safe, one can make it without to much issue imo.

Plus, you'd only have to make small amounts to support a habit. If one is at the point of making fent, they either have a habit or soon will.

 

[findus78]

Are you sure on this information about the potency of α-methylfentanyl, I have seen like 6 different sources all of them tell different strength, from 50x to 200x, 100x, 7000x morphine, I think the last source must have mistaken this one for 3-methyl-F. Wikipedia tells: α-Methylfentanyl has similar effects to fentanyl. It is less potent by weight due to reduced binding affinity to its target site

 

[reptilianeyes]

Have the right respirator, and filter canisters, (if you got a military chemical suit will be more efficient) BUT You need a control atmosphere with proper ventilation. A sidenote, the best time to do any synthesis with volitale or unpleasant smells is when the weather is raining and windy. Not only the wind disperse the gases but the rain absorbs the smells. Regardless do your research and make notes of reaction mixtures and always have a plan b and plan c just in case if the unexpected happens.

 

[middlemaneu]

If putting efforts and high potency is required, then why not doing the most euphoric and recreational ever made, cousin of car-f: R-30490 <3 (approx 380x morphine potency)
IMO all those high potencies especially for fentas are not needed. The outstanding BA with any RoA, and considering 98% of people got a lower tolerance than fent HCL - the best ones are the mid-potency that are well known like Acetyl-F, Furanyl-F (15x, 25x). Zenes brought this stupid business model thinking the stronger the better, but it's the receptors affinity that matters.

Comparing on a low-potency scale, dextromoramide is only 3.5x morphine potency but the most euphoric opioid known of this league. And Ketobemidone? It's even less than morphine potency, but when it was used initially as methadone replacement, most addicted came back asking for it and preferring it over heroin

But yeah, fent remains my fav class ever (not fent hcl or the most used from cartels, just potent but boring effect, like 4F-Fent and 4C-Fent)