Ephedrine extraction from plants

[Microogata]

Thank you very much for this information. I was wondering where I could get my hands on this Ephedra (or Ma-Huang) plant ?
Do you think that Alibaba is a good source to buy it from (since it comes from China) ? https://www.alibaba.com/trade/search?fsb=y&IndexArea=product_en&CatId=&SearchText=ma-huang

 

[cesc]

Hi. I ve bough close to 1kg on Xina, perhaps could I help u

 

[Reepicheep]

What is xina? You have a link?

 

[googie]

CN103833559A - Extraction process of ephedrine - Google Patents

The invention relates to an extraction process of ephedrine, and belongs to the technical field of extraction of effective components in traditional Chinese medicines. The process provided by the invention comprises the following steps: pretreatment of ephedra; alkalization; extraction with...

patents.google.com

In coming months I will attempt an extraction and post results.

 

[nobody66]

Hello brother, have you already tried it? What is the result? Have you succeeded in this method?

 

[roshan]

Can i use Ephedra gerardiana?

 

[googie]

Yes.

 

[9-Tryptophan]

I ordered 250g Ma Huang and tested the simple extraction with 25g.

I powdered it in the blender and extracted 1 part with ethanol and 1 part with IPA, dried both extracts at around 30°C and as expected, both extracts were green from chlorophyll and after concentrating and freezing nothing happened and after evaporating there was no white powder left behind but rather viscous green oil.

I thought if I extract this oil with Naptha and mix it well I can get the ephedrine from it. However, nothing happened when it was frozen and after the naptha had evaporated, only a black tar-like residue remained.

The last thing I tried was dissolving it in a little naptha and precipitating it with acetone, but that didn't work either.

It could also be that the Chinese sent me crap, but at least it looks like Ephedra sinica.

 

[DrGodMan]

non-polar solvents
petroleum => non-polar solvent ?

 

[Irving Langmuir]

Some time ago I tried an acid–base extraction on ephedra distachya because the ethanol extraction solubilizes chlorophyll and other junk.

It seems to have worked, as I was left with a white powder, but too small a quantity for it to be a viable source of ephedrine.

The ephedra distachya I got probably didn't have much ephedrine in it and I was kind of expecting it, or my work up sucked.

For those interested, here's a document on the properties of the different ephedrine salts

https://onlinelibrary.wiley.com/doi/epdf/10.1002/jps.20927

 

[Nikolas]

Hello friends, I have ephedra extract available in both powder and liquid form. Can I extract ephedrine from ephedra extract? What method do you recommend? Does it have to be dry plant powder?

 

[lapgan1]

Hello, can I use the white powder from step 1c obtained in the second extraction way to synthesize meth?

 

[handle]

Extracting ephedrine from Ephedra vulgaris is relatively simple. The leaves of the plant are dried and then ground into a powder.

This powder can then be added to water and boiled to create an extract. The ephedrine will precipitate out of the solution and can be collected and dried for later use.

 

[handle]

Here is a easy to follow step by step guide from plant to potency

Spoiler: STEP BY STEP GUIDE

5.1 Preparation of Plant Material
- Harvesting: Select mature plants from the sources mentioned earlier, ensuring they are free from contaminants.
- Cleaning: Thoroughly clean the plant material to remove dirt and debris.
- Drying: Dry the plant material to reduce moisture content, which is crucial for the extraction process.

5.2 Comminution
- Grinding: Grind the dried plant material into a fine powder to increase the surface area for better extraction.

5.3 Extraction Method
- Solvent Selection: Choose an appropriate solvent, such as methanol or ethanol, which can dissolve ephedrine effectively.
- Mixing: Mix the plant powder with the solvent in a suitable container, ensuring thorough contact between the solvent and plant material.
- Decoction: Heat the mixture gently to facilitate the extraction process. Monitor the temperature to avoid degradation of ephedrine.

5.4 Filtration
- Separation: After the extraction is complete, separate the liquid from the solid plant residue through filtration. Use a filter paper or cloth to ensure a clear liquid is obtained.

5.5 Evaporation
- Concentration: Evaporate the solvent from the liquid extract to concentrate the ephedrine. This can be done using a rotary evaporator or by gentle heating under a fume hood.

5.6 Crystallization
- Cooling: Cool the concentrated solution to promote the crystallization of ephedrine.
- Filtering Crystals: Once crystals have formed, filter them out using vacuum filtration to obtain pure ephedrine crystals.

5.7 Drying and Weighing
- Drying: Dry the ephedrine crystals thoroughly to remove any residual solvent.
- Weighing: Weigh the extracted ephedrine to determine the yield of the extraction process.

5.8 Quality Control
- Testing: Perform tests, such as thin-layer chromatography (TLC) or high-performance liquid chromatography (HPLC), to confirm the presence and purity of ephedrine in the extract.

 

[pigs4you]

What I don't understand is the crystallization.. .. I have never been able to achieve this!!

 

[pigs4you]

I even have a vaccum ethanol extractor, but Im afraid its getting too hot and destroying the ephedrine.

 

[handle]

Slow and low, slow and low.

 

[pigs4you]

Low temp? All I get is green crusty

 

[four4jhon]

I need methamphetamine

 

[Bmth]

Please help I bought a small amount of ma huang plants, To have to end up after being inflated with Hcl gas, producing a solid but not crystal (different from the extraction of the pill) I tried to taste a little less bitter in contrast to the pseudoephedrine from the pill? Is this really the epedra plant I bought or is it just weeds

 

[G.Patton]

Your question is unclear. I would like to help you but you write question, which can't be answered.
I bought some plant and get this. Is it okay or not? Try to read your message and think how can anyone understand your mind and way of thinking? I face such messy explanations every day....

 

[Bmth]

Sorry patton sir, just skip this for my question, and sorry for my poor/bad english