Example of isomer separation for Meth

[btcboss2022]

I forgot to clarify that to avoid long discussions sorry hahaha

L-tartaric acid CAS 87-69-4

 

[Bmth]

Hopefully it is true for this tartarat? Please helpHopefully it is true for this tartarat? Please help

 

[btcboss2022]

It works with MDMA freebase and Ketamine freebase too just changing ratios with molar weight of each freebase. Remember that in the MDMA and Ketamine case the interesting isomer will be in the solid part using these reagents ;-)

 

[riahisunak]

Hi,
You said this would work with MDMA and ketamkme , just use molar equivalents .
But your ratios don't match the the molar equivalents
3650÷149.2337=24.5 moles
24.5×150.09= 3670g of L tartaric
150.09mm L tartaric
149.2337mm M
??

 

[wael gano]

Good job great effort
I think it is better to add a nonpolar solvent and extract the nonpolar D base, since after alkalinizing the water, you collect the nonpolar base. Liquid/liquid extraction.

 

[Candyshop]

So you don't have to divide isomers with tartaric acid, if I cleaned the material after the reaction with toulene, a non-polar solvent ???

 

[Candyshop]

However, is it always necessary to separate the isomers in some way?????

 

[Sjeik]

It has to be like this..

 

[hunter12]

Nice, you used the same method?

 

[Sjeik]

I had like 700ml racemic fb, And after sepration got around 320ml d-fb.

 

[qwe111]

Hey man, this yields great!
Did you clean the L-fb and L-tartaric acid mixture inside the funnel during vacuum filtration? If so, what cleaning do you use? Then how to detach D-fb

 

[Sjeik]

No, i use an centrifuge

 

[Fringg]

Please, what kind of centrifuge do you use? I tried filtering using reduced pressure and a Buchner funnel, but the tartrate was still wet at the end and retained liquid. I got a little D-isomer at the end

 

[Fringg]

Hello, I greet you all. I want to share with you my experience with the separation of isomers using L-wine. I did three tests. 2x using methanol when I changed the ratio of free base methanol and tartaric acid in both tests. Both tests turned out basically the same, after combining the ingredients and mixing, a solid mass precipitated, which I filtered after 24 hours. As for the appearance of the product and the overall split isomers, perhaps there was a little more products in one test than in the other test. From 30ml of free base I got about 9 grams of d-meth. During evaporation, when the crystals started to appear, it looked good at first, small needles were formed here and there, but the drier it got, the more it resembled a racemate (ugly amorphous substance). When it dried completely, in terms of appearance, I could not tell the difference between the racemate and this divided product. When it was put on foil and warmed up a little, it was obvious that the crystals crystallize a little faster after dissolution than when it is done with the racemate. From this I concluded that some division took place, but not enough. I note that I did not wash the tartrate powder during filtering. It was not written in the procedure, so I preferred not to do it. Well, now we come to the third test, which I did with the help of water according to the btcboss procedure. After combining all the ingredients and mixing vigorously, after a while I got a thick, really thick mass resembling some kind of cream. It had a consistency basically like the photo that was added by the user Sjeik a couple of posts above mine. I closed the container and let it sit for 24 hours, then I put this substance in the filter and spread it over the vacuum filter and turned on the suction. This thick cream-like substance was really difficult to filter, also in the procedure there was nothing written about washing the tartrate in the filter, so I didn't do it. I only got 11 grams of product from 60ml of free base. But the crystals that arrived were transparent and beautiful. I tried melting them on tin foil to see how fast they solidify and it was really fast like pseudoephedrine meth. So I think that the Split izomer was successful except for the mass tragedy of only 11 grams. The problem was probably mainly that I had a bit of a problem during filtration with the fact that the funnel on the suction flask did not seal well and it might also help to wash off the tartrate salt during filtration, but please advise me how much water I can use for this so as not to disturb the solubility of the tartrate in water and thus did not get L isomers into the product. Well thank you

 

[Acab1312]

Repeat the isomeric separation for a higher yield.

Freebase the failed salt and repeat process

- Wash it with cold anhydrous methanol, the L-meth/tartaric acid mixture is not soluble in methanol.

 

[Fringg]

Thanks, I'll try and let you know. Please, what temperature should methanol be, just put it in the fridge or should I use the freezer instead

 

[Acab1312]

I would recommend the freezer. In this case, the colder the better. The temperatures were never measured, I always store my methanol in the freezer.

-The polarity (polarimeter tested) after one pass

- H20 (68-73% d)

- Methanol (71-76% d)

- Rusznak process, toluene as a benzene substitute (still failed racemic)

- Pope - Peachey : h20/hydrochloric acid
(65-80 % d is time-dependent)

I prefer the method with h20 because of cost, time and simplicity.

I hope I could help.

 

[chef learner]

After I separated the L-tartaric acid isomers, I mixed the methanol and coagulated tartaric acid, filtered out the solid, retained the liquid part, and then added NaOH aqueous solution to obtain D-FB. Everything went smoothly. I took it out. After the D-FB in the upper layer, there is the NaOH water/methanol solution in the lower layer. This layer should be waste. Because I was busy at work, I forgot to discard this layer of waste liquid. The next day it turned into crystals. You can ask what is crystallizing here. Is it? Is the sodium hydroxide recrystallized? The crystals are needle-shaped and abundant. I don’t understand chemistry, so I don’t know the reason for this formation and what its ingredients are.

 

[Gustavoo]

I think it's sodium hydroxide or some kind of tartrate. If you want to check if there is any product left in the aqueous solution, add more aqueous hydroxide and pour in more toulen or any other solvents you like. Show what d-meth crystals you got after recrystallization.
Also how many of what amount of fb