Бромирование 4-метилпропиофенона с использованием NBS/PTSA и в условиях отсутствия растворителя (крупномасштабное)

[whitelabel]

And once dried under airflow, is the 2b4m good quality also how can it be stored

 

[Miś.Didi]

Yes later u need only made crystal 2b4m on dcm this all

 

[Miś.Didi]

Only when use brom then you can do it

 

[Miś.Didi]

Only when use brom then you can do it

 

[whitelabel]

Heat to 40deg c with DCM and refrigerate?

 

[Miś.Didi]

U can

 

[whitelabel]

To proceed with 4mmc using EA and ma40 , do we need to crystallize the crude 2b4m we get from this method as listed originally??

 

[whitelabel]

Or I rather stick to benzene bromine method from 4mp which always works but requires large volumes