Bromination would be easier to do in a flask with a side neck, from which gaseous acid must enter the container with the absorber. For methylamination, you can use a HDPE canister with a tight-fitting stopper. Methylamine can be safely added in a trickle, the main thing is that the reaction mass does not start to boil. After adding all the methylamine, it is necessary to close the stopper and stir until the reaction mixture cools down. Then the synthesis can be considered complete. The emerald green color in the third picture indicates that there is too much unreacted 2-bromo-4-methilpropiophenone. In this case, it is necessary to distill the reaction mass with steam and separate the unreacted 2-bromo-4-methilpropiophenone, if this is not done, the product will acquire a color that will be difficult to wash. This will also get rid of the remaining methylamine. When laying 1.4 kg 2-bromo-4-methilpropiophenone you will not be able to simply take a glass rod and stir the acid in the base. A top drive agitator or similar device must be used. It is desirable to cool the reaction mass. A separatory funnel can then be used to supply the acid.
4-MMC (mephedrone) synthesis. Bromination in dichlormethane.
Looks nice. Only ideal conditions for bromination need to be changed. The easiest way to brominate with virtually no odor is to brominate in DCM under a layer of water. Water absorbs hydrogen bromide, thus the smell and gases are practically absent in the external environment.
Thus, 50-100 liters of ketone can be brominated at a time.
Thus, 50-100 liters of ketone can be brominated at a time.
- By whitelabel
So dcm plus 4mp heated stirred and then water added before bromine addition?
Is any hcl addition helpful at the beginning? Say 50ml 37%?
The bromine will need to be mixed with dcm or another solvent o go in the dropping funnel?
The bromine mix is dropped on the water but reacts with rm with over head stirring?
Is any hcl addition helpful at the beginning? Say 50ml 37%?
The bromine will need to be mixed with dcm or another solvent o go in the dropping funnel?
The bromine mix is dropped on the water but reacts with rm with over head stirring?
Also, an interesting and important question. 4MMC powder and 4MMC crystals - are they, in structure and action on the brain somehow different? Are they more effective, mg per mg? Or is it just visual effect and assurance of consumers that the crystals, instead of powder, cannot be tampered with and cut?
I remember that back in the day, prior to the age of 3MMC and then 3CMC, mephedrone was often sold in both forms, for the same price (more or less), and many people often somewhy preferred the powdered form?
Does the potency increase once the powder is crystalised? Or it's effects are the same, gram of powder equating to gram of crystal?
A very interesting and important question that I would appreciate the professionals to answer.
Cheers.
I remember that back in the day, prior to the age of 3MMC and then 3CMC, mephedrone was often sold in both forms, for the same price (more or less), and many people often somewhy preferred the powdered form?
Does the potency increase once the powder is crystalised? Or it's effects are the same, gram of powder equating to gram of crystal?
A very interesting and important question that I would appreciate the professionals to answer.
Cheers.
- By TheVacuumGuy
Crystallization is a technique to purify the product.
The effects are the same. However crystals are more attractive and this way is to be received (brain workings) more intense (less impure)
The effects are the same. However crystals are more attractive and this way is to be received (brain workings) more intense (less impure)
- By TheVacuumGuy
Reading this back.. have to add that crystals ARE more pure ofcourse.
But effect-wise theres no diff in doing eg. 0.8g of crystals or 1.2g of powder. Although dirty taste might diminish it for some. But please do everyone a favor and just make crystals.
But effect-wise theres no diff in doing eg. 0.8g of crystals or 1.2g of powder. Although dirty taste might diminish it for some. But please do everyone a favor and just make crystals.